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Two new alcohol glycosides from the roots of Paeonia intermedia C. A. Meyer.

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机构: [1]School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China [2]Collaborative Innovation Center of Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China [3]Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou 510632, China
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关键词: Ranunculaceae Paeonia intermedia alcohol glycoside antibacterial activity

摘要:
Two new alcohol glycosides, 1-O-β-d-glucopyranosyl-deoxypaeonisuffrone (1) and 9-O-β-d-apiofuranoyl-(1→6)-β-d-glucopyranosyl-xanthoarnol (2), together with eight known compounds (3-10), have been isolated from the dried roots of Paeonia intermedia C. A. Meyer. Their structures were mainly elucidated on the basis of ESIMS, one- and two-dimensional NMR techniques. Antibacterial activities of compounds 1-10 were evaluated, and compounds 9 and 10 showed antibacterial activities against Staphylococcus argenteus CMCC26003 and Escherichia coli CMCC44103.

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出版当年[2020]版:
大类 | 4 区 医学
小类 | 4 区 植物科学 4 区 应用化学 4 区 药物化学 4 区 药学
最新[2023]版:
大类 | 3 区 医学
小类 | 4 区 应用化学 4 区 药物化学 4 区 药学 4 区 植物科学
第一作者:
第一作者机构: [1]School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China
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通讯作者:
通讯机构: [1]School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China [3]Institute of Traditional Chinese Medicine & Natural Products, Jinan University, Guangzhou 510632, China
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