Two new compounds, named leptospyranonaphthazarin A (1) and leptosnaphthoic acid A (2), together with four known compounds (3-6) were isolated from an endophytic fungus Leptosphaerulina sp. SKS032. Their structures were assigned using spectroscopic methods, computational methods, and single-crystal X-ray diffraction analysis. In the antibiotic assay, compounds 1, 2, and 6 exhibited antibacterial activities against Staphylococcus aureus with minimal inhibitory concentration (MIC) values of 25.0, 50.0, and 50.0 mu g/mL, respectively.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [21472251, 41276146]; Science & Technology Plan Project of Guangdong Province of China [2013B021100011]; Key Project of Natural Science Foundation of Guangdong ProvinceNational Natural Science Foundation of Guangdong Province [2016A040403091]; Special Financial Fund of Innovative Development of Marine Economic Demonstration Project [GD2012-D01-001]; China Postdoctoral Science Foundation Funded ProjectChina Postdoctoral Science Foundation [2013M542223]; China's Marine Commonwealth Research Project [201305017]
语种：
外文
被引次数：
WOS：
中科院(CAS)分区：
出版当年[2017]版：
大类|4 区生物
小类|4 区药物化学4 区植物科学
最新[2023]版：
大类|4 区生物学
小类|4 区药物化学4 区植物科学
第一作者：
第一作者机构：[1]Sun Yat Sen Univ, Sch Chem, Guangzhou 510275, Guangdong, Peoples R China;
通讯作者：
通讯机构：[1]Sun Yat Sen Univ, Sch Chem, Guangzhou 510275, Guangdong, Peoples R China;
推荐引用方式(GB/T 7714)：
Cui Hui,Liu Yena,Ding Meng,et al.New pyranonaphthazarin and 2-naphthoic acid derivatives from the mangrove endophytic fungus Leptosphaerulina sp SKS032[J].PHYTOCHEMISTRY LETTERS.2017,20:214-217.doi:10.1016/j.phytol.2017.05.010.
APA：
Cui, Hui,Liu, Yena,Ding, Meng,Zhang, Zhengrui,Liu, Huiting...&She, Zhigang.(2017).New pyranonaphthazarin and 2-naphthoic acid derivatives from the mangrove endophytic fungus Leptosphaerulina sp SKS032.PHYTOCHEMISTRY LETTERS,20,
MLA：
Cui, Hui,et al."New pyranonaphthazarin and 2-naphthoic acid derivatives from the mangrove endophytic fungus Leptosphaerulina sp SKS032".PHYTOCHEMISTRY LETTERS 20.(2017):214-217
