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Cellphone remote intelligent neuroregulation with self-powered piezoelectric wireless brain probe

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机构: [1]Univ Elect Sci & Technol China, Sch Phys Elect, Chengdu 611731, Peoples R China [2]Chinese Acad Sci, Brain Cognit & Brain Dis Inst, Shenzhen Inst Adv Technol, Shenzhen 518055, Peoples R China [3]City Univ Hong Kong, Dept Mech Engn, Kowloon, 83 Tat Chee Ave, Hong Kong 999077, Peoples R China [4]Univ Elect Sci & Technol China, Sch Informat & Commun Engn, Chengdu 611731, Peoples R China [5]Univ Elect Sci & Technol China, Sch Elect Sci & Engn, Chengdu 611731, Peoples R China [6]Univ Elect Sci & Technol China, Sichuan Canc Hosp & Inst, Canc Hosp affiliate, Sichuan Canc Ctr,Sch Med, Chengdu 610041, Peoples R China
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关键词: Self -powered Wireless -control Brain probe Artificial intelligence Remote precision neural modulation Piezoelectric effect

摘要:
The neural regulation that is tele-controlled remotely by medical professionals or artificial intelligence (AI) agents can meet the requirement of rapid, precise, personalized intervention and optimize the allocation of medical resources. Here, we develop a new self-powered wireless mini-invasive brain probe for remote intelligent neuroregulation. The probe can be wirelessly powered and controlled by cellphone audio tones (through piezoelectric effect) with the assistance of AI cellphone video analysis. The probe consists of a biocompatible pedestal integrated with implanting stimulation electrodes connected to embedded magnets and a magnetically coupled custom-designed signal-intensifying resonator integrated with a piezoelectric powered signal modula-tion circuit. A programmed audio tone functions as the wireless power source, and it can be tele-transmitted remotely from other cellphones with desired neural stimulation protocols. Combined with AI-enabled video monitoring of the epileptic tremor, we show that the probe can relieve the seizure events in the epileptic mice, and the therapeutic effect is confirmed by in-vivo electroencephalography and free-moving scenario. The multi -functionality of versatility, AI-assistance, wireless power transfer, and tele-transmission of the cellphone-interacted brain probe opens the possibility for remote precision neural modulation.

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出版当年[2023]版:
大类 | 1 区 材料科学
小类 | 1 区 物理化学 1 区 材料科学:综合 1 区 纳米科技 1 区 物理:应用
最新[2023]版:
大类 | 1 区 材料科学
小类 | 1 区 物理化学 1 区 材料科学:综合 1 区 纳米科技 1 区 物理:应用
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出版当年[2023]版:
Q1 CHEMISTRY, PHYSICAL Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Q1 NANOSCIENCE & NANOTECHNOLOGY Q1 PHYSICS, APPLIED
最新[2023]版:
Q1 CHEMISTRY, PHYSICAL Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY Q1 NANOSCIENCE & NANOTECHNOLOGY Q1 PHYSICS, APPLIED

影响因子: 最新[2023版] 最新五年平均 出版当年[2023版] 出版当年五年平均 出版前一年[2022版]

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第一作者机构: [1]Univ Elect Sci & Technol China, Sch Phys Elect, Chengdu 611731, Peoples R China
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