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Chinese Expert Consensus on the Clinical Applications of Aminolevulinic Acid-Based Photodynamic Therapy in Female Lower Genital Tract Diseases (2022)

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机构: [1]Department of Obstetrics and Gynecology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. [2]Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, China. [3]Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Beijing, China. [4]Department of Obstetrics and Gynecology, Zhujiang Hospital, Southern Medical University, Guangzhou, China. [5]Department of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, China. [6]Department of Obstetrics and Gynecology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. [7]Department of Obstetrics and Gynecology, Beijing Hospital, Beijing, China. [8]Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, China. [9]Department of Obstetrics and Gynecology, International Peace Maternity & Child Health Hospital of China Welfare Institute, Shanghai, China. [10]Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, Jinan, China. [11]Department of Obstetrics and Gynecology, Affiliated Hospital, Nantong University, Nantong, China. [12]Department of Obstetrics and Gynecology, The First Affiliated Hospital, Zhengzhou University, Zhengzhou, China. [13]Department of Obstetrics and Gynecology, Xiangya Hospital, Central South University, Changsha, China. [14]Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China. [15]Department of Obstetrics and Gynecology, Naijing Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, China. [16]Department of Obstetrics and Gynecology, The First Affiliated Hospital, Anhui Medical University, Hefei, China. [17]Department of Obstetrics and Gynecology, Anhui Provincial Hospital, University of Science and Technology of China, Hefei, China [18]Department of Obstetrics and Gynecology, Anhui Provincial Cancer Hospital, Hefei, China [19]Department of Obstetrics and Gynecology, Guangdong Province Traditional Chinese Medical Hospital, Guangzhou, China [20]Department of Obstetrics and Gynecology, Zhongda Hospital, Southeast University, Nanjing, China [21]Department of Obstetrics and Gynecology, Shanghai Sixth People’s Hospital, Shanghai Jiaotong University, Shanghai, China [22]MOE Key Laboratory of OptoElectronic Science and Technology for Medicine, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Normal University, Fuzhou, China [23]Department of Obstetrics and Gynecology, Obstetrics & Gynecology Hospital, Fundan University Shanghai, China
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关键词: Female lower genital tract diseases ALA PDT Consensus

摘要:
With the younger onset age of female lower genital tract diseases, there are increasing demands for protecting organ and tissue structures to preserve fertility and, therefore, effective fertility-sparing treatments that cause minimal normal tissue damage and less adverse reactions are urgently needed.This study is aimed at reviewing information and achieving consensus on recommendations on the clinical applications of aminolevulinic acid-based photodynamic therapy (ALA-PDT) in female lower genital tract diseases.Members of the expert panel held online and in-person meetings to discuss and revise drafts created by the steering committee based on the literature review and the clinical experiences of the expert panel. Opinions of the experts were transcribed and discussed in detail to ensure that the consensus statement best reflects the current advances in the field and the experts' view.After numerous rounds of meetings, experts unanimously agreed on the importance of ALA-PDT in the treatment of cervical squamous intraepithelial lesions (SIL), vaginal SIL, vulvar SIL, vulvar lichen sclerosus (VLS), and condyloma acuminatumon (CA). Experts also reached consensus on the recommended treatment regimen and treatment methods.This consensus aimed to provide practical basis and guidance for the clinical applications of ALA-PDT in female lower genital tract diseases in China. Of note, this is the only expert consensus prepared by board-certified specialists in gynecology and obstetrics in China. More evidence-based clinical studies should be made to update and expand the current recommendations.Copyright © 2022. Published by Elsevier B.V.

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出版当年[2022]版:
大类 | 3 区 医学
小类 | 4 区 肿瘤学
最新[2023]版:
大类 | 3 区 医学
小类 | 4 区 肿瘤学
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Q3 ONCOLOGY
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Q2 ONCOLOGY

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第一作者机构: [1]Department of Obstetrics and Gynecology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
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