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Chinese expert consensus on hematologic malignancy karyotyping

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WOS体系：
Pubmed体系：

收录情况： ◇ SCIE

作者：
Yang, Zailin[1] * ; Chen, Shuang[1] ; Zhao, Mingyu[1] ; Gao, Fei[2] ; Li, Jianwei[3] ; Peng, Yu[1] ; Jiang, Tingting[1] ; Zhang, Jun[4] ; Tang, Xinyi[1,5] ; Zhang, Yakun[1,5] ; Chen, Fan[6] ; Chen, Hongwei[7] ; Chen, Pu[8] ; Chen, Siyu[9] ; Huang, Xingqin[10] ; Jia, Yujiao[11] ; Xie, Xiaohong[12] ; Li, Chengwen[11] ; Li, Guoxia[13] ; Li, Jieping[1] ; Li, Zhaoquan[14] ; Li, Zheng[15] ; Liang, Rong[16] ; Liu, Jie[17] ; Liu, Ling[18] ; Long, Fang[19] ; Long, Zhigao[20] ; Lue, Jinglong[12] ; Ma, Qiang[21] ; Mao, Ping[22] ; Pan, Bin[23] ; Pan, Jinlan[24] ; Pan, Ling[25] ; Peng, Xiangui[9] ; Qiang, Xing[9] ; Ran, Longrong[1] ; Ren, Fanggang[26] ; Sun, Xiuhua[27] ; Wang, Dangfeng[28] ; Wang, Li[29] ; Wang, Shiyi[30] ; Wang, Xingzhe[31] ; Wang, Yanfang[32] ; Wang, Ying[33] ; Wang, Zhiyuan[23] ; Wei, Xia[34] ; Wu, Zhiwei[35] ; Wu, Menghua[6] ; Wu, Xuelian[1] ; Xiao, Jianwen[36] ; Yang, Junjun[37] ; Yang, Zesong[14] ; Yao, Yuanyou[10] ; Ying, Yi[22] ; Yu, Yalan[38] ; Zhang, Meiling[39] ; Zhang, Ping[40] ; Zhang, Wei[41] ; Zhou, Hui[42] ; Zhou, Jianfeng[6] ; Zhu, Mingxia[32] ; Zou, Liqun[43] ; Mao, Cui[3] ; Yang, Ximing[44] ; Liu, Yao[1] ;
机构： [1]Chongqing Univ, Canc Hosp, Dept Hematol Oncol, Chongqing 400030, Peoples R China [2]Sichuan Kingmed Ctr Clin Lab CO Ltd, Dept Cytogenet, Si Chuan, Peoples R China [3]Tianjin Kingmed Ctr Clin Lab CO Ltd, Dept Cytogenet, Tianjin, Peoples R China [4]First Affiliated Hosp Soochow Univ, Jiangsu Inst Hematol, Suzhou, Jiangsu, Peoples R China [5]Chongqing Univ, Sch Med, Chongqing 400044, Peoples R China [6]Guangzhou KingMed Ctr Clin Lab Co Ltd, Dept Special Inspect, Guangzhou 510000, Peoples R China [7]First Hosp Qinhuangdao, Dept Clin Lab, Qinhuangdao 066000, Peoples R China [8]Fudan Univ, Zhongshan Hosp, Dept Lab Med, Shanghai 200032, Peoples R China [9]Third Mil Med Univ, Army Med Univ, Xinqiao Hosp, Clin Med Res Ctr, Chongqing 400037, Peoples R China [10]Third Mil Med Univ, Army Med Univ, Southwest Hosp, Dept Hematol, Chongqing 400038, Peoples R China [11]Chinese Acad Med Sci & Peking Union Med Coll, Inst Hematol & Blood Dis Hosp, Tianjin 300020, Peoples R China [12]Chongqing Univ Three Gorges Hosp, Dept Pathol, Chongqing 404100, Peoples R China [13]Second Hosp Shanxi Med Univ, Inst Hematol, Taiyuan 030001, Peoples R China [14]First Affiliated Hosp Chongqing Med Univ, Dept Gastroenterol, Chongqing 400016, Peoples R China [15]Army Med Univ, Army Specialty Med Ctr, Dept Gastroenterol, 10 Changjiangzhi Rd, Chongqing 400042, Peoples R China [16]Air Force Med Univ, Xijing Hosp, Dept Pathol, Xian 710032, Peoples R China [17]Xuzhou Med Univ, Sch Med Informat & Engn, Dept Intelligent Med Lab, Xuzhou, Jiangsu, Peoples R China [18]Shanxi Dayi Hosp, Taiyuan 030000, Peoples R China [19]Third Mil Med Univ Army Med Univ, Southwest Hosp, Dept Prevent & Healthcare, 30 Gaotanyan Rd, Chongqing 400038, Peoples R China [20]Cent South Univ, Ctr Med Genet, Sch Life Sci, Changsha 410078, Peoples R China [21]North Sichuan Med Coll, Dept Clin Lab, Affiliated Hosp, Nanchong 637000, Peoples R China [22]Guangzhou First Peoples Hosp, Dept Hematol, Guangzhou 510180, Peoples R China [23]Affiliated Hosp Xuzhou Med Univ, Dept Hematol, Xuzhou 221002, Peoples R China [24]Suzhou Univ, Dept Orthoped, Affiliated Hosp 1, Suzhou 215000, Peoples R China [25]Sichuan Univ, West China Hosp, Dept Hematol, Chengdu 610041, Peoples R China [26]Second Hosp Shanxi Med Univ, Dept Orthoped, Taiyuan 030001, Shanxi, Peoples R China [27]Wuhan Univ, Renmin Hosp, Dept Head & Neck Oncol Lymphoma & Pediat Oncol, Wuhan, Peoples R China [28]Beijing Changping Dist Hosp, Dept Radiol, Beijing 102200, Peoples R China [29]Shanghai Jiao Tong Univ Sch Med, Ruijin Hosp, Natl Res Ctr Translat Med Shanghai, Shanghai Inst Hematol,State Key Lab Med Genom, Shanghai 200025, Peoples R China [30]Chongqing Med Univ, Dept Clin Lab, Childrens Hosp, Chongqing 400014, Peoples R China [31]Second Hosp Hebei Med Univ, Hebei Key Lab Lab Med, Shijiazhuang 050000, Hebei, Peoples R China [32]Peking Univ Third Hosp, Dept Hematol, Beijing, Peoples R China [33]Huazhong Univ Sci & Technol, Tongji Med Coll, Clin Lab, Tongji Hosp, Wuhan 430030, Peoples R China [34]Chongqing Med Univ, Dept Obstet & Gynecol, Third Affiliated Hosp, Chongqing 401120, Peoples R China [35]First Affiliated Hosp USTC, Dept Endocrinol, Lab Diabet, Hefei 230001, Anhui, Peoples R China [36]Chongqing Med Univ, Dept Hepatol, Childrens Hosp, Chongqing 400016, Peoples R China [37]Wenzhou Med Univ, Sch Lab Med & Life Sci, Wenzhou 325000, Peoples R China [38]Wuhan Univ, Dept Hematol, Zhongnan Hosp, Wuhan 430071, Peoples R China [39]Clin Lab Co Ltd, Zhengzhou KingMed Ctr, Zhengzhou, Peoples R China [40]Second Affiliated Hosp Chongqing Med Univ, Dept Gastroenterol, Chongqing 400010, Peoples R China [41]Peking Union Med Coll Hosp, Dept Hematol, Beijing 100730, Peoples R China [42]Cent South Univ, Affiliated Canc Hosp, Hunan Canc Hosp, Xiangya Sch Med, Changsha 410013, Peoples R China [43]Sichuan Univ, West China Hosp, Canc Ctr, Dept Med Oncol, Chengdu 610041, Peoples R China [44]Beijing Univ Chinese Med, Dongzhimen Hosp, Dept Clin Lab, 5 Haiyuncang, Beijing 100700, Peoples R China
出处：
DOI： 10.1016/j.cca.2025.120507
ISSN：

关键词： Chromosome Karyotype analysis Cytogenetics Chromosome banding Hematologic malignancies

摘要：
Chromosomal karyotype analysis is crucial for diagnosing and managing hematologic malignancies, yet inconsistent protocols compromise reliability. To standardize practices, this consensus integrates international guidelines (WHO, ICC, ELN) with clinical expertise, providing evidence-based recommendations for specimen collection, cell culture, chromosome harvesting, banding techniques, karyotype analysis, and reporting. By establishing uniform operational standards, this initiative seeks to mitigate variability, improve detection rates, and support precision medicine in hematologic malignancies.

基金：
Fundamental Research Funds for the Central Universities of China [2022CDJYGRH-001]; Chongqing Technology Innovation and Application Development Special Key Project [CSTB2024TIAD-KPX0031]; Chongqing Science and Health Joint Project [2025DBXM002]
语种：
外文
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2026]版：
无
最新[2025]版：
大类 | 3 区 医学
小类 | 3 区 医学实验技术
JCR分区：
出版当年[2026]版：
无
最新[2024]版：
Q2 MEDICAL LABORATORY TECHNOLOGY

影响因子： 最新[2024版] 最新五年平均 出版当年[2025版] 出版当年五年平均 出版前一年[2025版]

第一作者：
第一作者机构： [1]Chongqing Univ, Canc Hosp, Dept Hematol Oncol, Chongqing 400030, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Yang Zailin,Chen Shuang,Zhao Mingyu,et al.Chinese expert consensus on hematologic malignancy karyotyping[J].CLINICA CHIMICA ACTA.2026,578:doi:10.1016/j.cca.2025.120507.
APA：
Yang, Zailin,Chen, Shuang,Zhao, Mingyu,Gao, Fei,Li, Jianwei...&Liu, Yao.(2026).Chinese expert consensus on hematologic malignancy karyotyping.CLINICA CHIMICA ACTA,578,
MLA：
Yang, Zailin,et al."Chinese expert consensus on hematologic malignancy karyotyping".CLINICA CHIMICA ACTA 578.(2026)

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