机构:[1]Chengdu Univ Tradit Chinese Med, Sch Pharm, State Key Lab Southwestern Chinese Med Resources, Chengdu, Peoples R China[2]Univ Elect Sci & Technol China, Sch Med, Sichuan Canc Ctr, Sichuan Canc Hosp & Inst,Dept Clin Pharm, Chengdu, Peoples R China临床药学部临床药学部四川省肿瘤医院[3]Univ Massachusetts, Dept Food Sci, Amherst, MA 01003 USA[4]USDA, Agr Res Serv, Southern Reg Res Ctr, New Orleans, LA USA
The importance of the "gut-liver axis" in the pathogenesis of liver diseases has been revealed recently; which promotes the process of developing preventive and therapeutic strategies. However, considering that there are still many challenges in the medical treatment of liver diseases, potential preventive dietary intervention may be a good alternative choice. Plant-based foods have received much attention due to their reported health-promoting effects in targeting multiple pathways involved in the pathogenesis of liver diseases as well as the relative safety for general use. Based on the PubMed and Web of Science databases, this review emphatically summarizes the plant-based foods and their chemical constituents with reported effects to impact the LPS/TLR4 signaling pathway of gut-liver axis of various liver diseases, reflecting their health benefits in preventing/alleviating liver diseases. Moreover, some plant-based foods with potential gut-liver effects are specifically analyzed from the reported studies and conclusions. This review intends to provide readers an overview of the current progress in the field of this research topic. We expect to see more hepatoprotective measures for alleviating the current prevalence of liver diseases.
基金:
National Natural Science Foundation of China [82073994]; Outstanding Young Scientific and Technological Talents Project of Science and Technology Department of Sichuan Province [2020JDJQ0049]; Key Open Fund of Key Laboratory of Coarse Grain Processing, Ministry of Agriculture [2019CC02]; International Cooperation Project of Science and Technology Department of Sichuan Province [2018HH0122]; Chengdu Science and Technology Bureau International Science and Technology Cooperation Project [2017-GH02-00054-HZ]; Xinglin Scholars Research Enhancement Program [QJJJ2021002, QNXZ2018026]; Chun-Hui Research Project of Ministry of Education of China [20191083-127]; USDA-ARS Quality and Utilization of Agricultural Products National Program [CRIS 6054-41000-113-00-D]
第一作者机构:[1]Chengdu Univ Tradit Chinese Med, Sch Pharm, State Key Lab Southwestern Chinese Med Resources, Chengdu, Peoples R China
通讯作者:
推荐引用方式(GB/T 7714):
Hu Qiongdan,Liao Wan,Zhang Zhen,et al.The hepatoprotective effects of plant-based foods based on the "gut-liver axis": a prospective review[J].CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION.2023,63(28):9136-9162.doi:10.1080/10408398.2022.2064423.
APA:
Hu, Qiongdan,Liao, Wan,Zhang, Zhen,Shi, Sanjun,Hou, Shuguang...&Li, Rui.(2023).The hepatoprotective effects of plant-based foods based on the "gut-liver axis": a prospective review.CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION,63,(28)
MLA:
Hu, Qiongdan,et al."The hepatoprotective effects of plant-based foods based on the "gut-liver axis": a prospective review".CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION 63..28(2023):9136-9162