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Unveiling the Impact of BMP9 in Liver Diseases: Insights into Pathogenesis and Therapeutic Potential

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机构: [1]Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, China. [2]Laboratory of Infectious and Liver Diseases, Institute of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, China. [3]Department of Gastroenterology, Kanazawa University Hospital, Kanazawa 9208641, Japan.
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关键词: BMP9 BMP signaling liver disease liver fibrosis liver cancer

摘要:
Bone morphogenetic proteins (BMPs) are a group of growth factors belonging to the transforming growth factor β(TGF-β) family. While initially recognized for their role in bone formation, BMPs have emerged as significant players in liver diseases. Among BMPs with various physiological activities, this comprehensive review aims to delve into the involvement of BMP9 specifically in liver diseases and provide insights into the complex BMP signaling pathway. Through an enhanced understanding of BMP9, we anticipate the discovery of new therapeutic options and potential strategies for managing liver diseases.

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最新[2023]版:
大类 | 2 区 生物学
小类 | 3 区 生化与分子生物学
第一作者:
第一作者机构: [1]Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, China. [2]Laboratory of Infectious and Liver Diseases, Institute of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, China.
通讯作者:
通讯机构: [1]Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, China. [2]Laboratory of Infectious and Liver Diseases, Institute of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, China.
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