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The Multifaceted Role of Long Non-Coding RNA in Gastric Cancer: Current Status and Future Perspectives.

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收录情况： ◇ SCIE

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机构： [1]Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, Sichuan, China. [2]South Sichuan Institute of Translational Medicine, Luzhou 646000, Sichuan, China. [3]Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province,Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu 610106, Sichuan, China. [4]Department of Pharmacy, the Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China. [5]Department of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen 518000, Guangzhou, China.

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关键词： long non-coding RNA gastric cancer drug resistance helicobacter pylori tumor microenvironment

摘要：

Gastric cancer (GC) is one of the major public health concerns. Long non-coding RNAs (lncRNAs) have been increasingly demonstrated to possess a strong correlation with GC and play a critical role in GC occurrence, progression, metastasis and drug resistance. Many studies have shed light on the understanding of the underlying mechanisms of lncRNAs in GC. In this review, we summarized the updated research about lncRNAs in GC, focusing on their roles in Helicobacter pylori infection, GC metastasis, tumor microenvironment regulation, drug resistance and associated signaling pathways. LncRNAs may serve as novel biomarkers for diagnosis and prognosis of GC and potential therapeutic targets. The research gaps and future directions were also discussed.© The author(s).

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出版当年[2021]版：

大类 | 2 区生物学

小类 | 2 区生化与分子生物学

最新[2023]版：

大类 | 2 区

生物学

小类 | 2 区生化与分子生物学

JCR分区：

出版当年[2021]版：

Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

最新[2023]版：

Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

影响因子： 8.2 最新[2023版] 8.3 最新五年平均 10.75 出版当年[2021版] 9.445 出版当年五年平均 6.582 出版前一年[2020版] 9.2 出版后一年[2022版]

第一作者：

第一作者机构： [1]Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, Sichuan, China. [2]South Sichuan Institute of Translational Medicine, Luzhou 646000, Sichuan, China.

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通讯作者：

通讯机构： [1]Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, Sichuan, China. [2]South Sichuan Institute of Translational Medicine, Luzhou 646000, Sichuan, China. [*1]Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou 646000, Sichuan, China.

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