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Multi-Dimensional Printing for Bone Tissue Engineering.

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机构： [1]Department of Bioengineering, Center for Minimally Invasive Therapeutics (C-MIT), California NanoSystems Institute, University of California, Los Angeles, CA 90095, USA [2]Stomatology Hospital, School of Stomatology, School of Medicine, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Clinical Research Center of Oral Disease of Zhejiang Province, Zhejiang University, Hangzhou, Zhejiang 310006, China [3]Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095, USA [4]School of Nursing, Nanjing University of Chinese Medicine, Nanjing 210023, China [5]State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China [6]Terasaki Institute for Biomedical Innovation, Los Angeles, CA 90064, USA [7]Jonsson Comprehensive Cancer Center, Department of Radiology, University of California, Los Angeles, CA 90095, USA

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关键词： 3D printing 4D printing bone drug delivery tissue engineering

摘要：

The development of 3D printing has significantly advanced the field of bone tissue engineering by enabling the fabrication of scaffolds that faithfully recapitulate desired mechanical properties and architectures. In addition, computer-based manufacturing relying on patient-derived medical images permits the fabrication of customized modules in a patient-specific manner. In addition to conventional 3D fabrication, progress in materials engineering has led to the development of 4D printing, allowing time-sensitive interventions such as programed therapeutics delivery and modulable mechanical features. Therapeutic interventions established via multi-dimensional engineering are expected to enhance the development of personalized treatment in various fields, including bone tissue regeneration. Here, recent studies utilizing 3D printed systems for bone tissue regeneration are summarized and advances in 4D printed systems are highlighted. Challenges and perspectives for the future development of multi-dimensional printed systems toward personalized bone regeneration are also discussed. © 2021 Wiley-VCH GmbH.

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出版当年[2021]版：

大类 | 2 区材料科学

小类 | 2 区工程：生物医学 2 区纳米科技 2 区材料科学：生物材料

最新[2023]版：

大类 | 2 区

医学

小类 | 2 区工程：生物医学 2 区材料科学：生物材料 2 区纳米科技

第一作者：

第一作者机构： [1]Department of Bioengineering, Center for Minimally Invasive Therapeutics (C-MIT), California NanoSystems Institute, University of California, Los Angeles, CA 90095, USA [2]Stomatology Hospital, School of Stomatology, School of Medicine, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Clinical Research Center of Oral Disease of Zhejiang Province, Zhejiang University, Hangzhou, Zhejiang 310006, China

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通讯作者：

通讯机构： [1]Department of Bioengineering, Center for Minimally Invasive Therapeutics (C-MIT), California NanoSystems Institute, University of California, Los Angeles, CA 90095, USA [3]Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095, USA [6]Terasaki Institute for Biomedical Innovation, Los Angeles, CA 90064, USA [7]Jonsson Comprehensive Cancer Center, Department of Radiology, University of California, Los Angeles, CA 90095, USA

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Multi-Dimensional Printing for Bone Tissue Engineering.

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