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Morphological Differences Between the Pedicles in Nondystrophic Scoliosis Secondary to Neurofibromatosis Type 1 and Those in Adolescent Idiopathic Scoliosis.

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机构： [1]Institute of Spinal Deformity, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, P. R. China. [2]Department of Orthopaedic Surgery and Orthopaedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan 610000, P. R.China. [3]Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, P. R. China. [4]Institute of Spinal Deformity, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, P. R. China. [5]Institute of Spinal Deformity, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, P. R. China.

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关键词： abnormal pedicle accuracy of pedicle screw placement nondystrophic scoliosis secondary to neurofibromatosis type 1 adolescent idiopathic scoliosis

摘要：

To compare the pedicle morphology of nondystrophic scoliosis secondary to neurofibromatosis type 1 (ND-NF1) scoliosis secondary to neurofibromatosis type 1 (NF1-S) and adolescent idiopathic scoliosis (AIS) using computed tomography (CT) in a consistent classification system. The transverse pedicle widths of cancellous and cortical channels were measured using preoperative spinal CT images (T1-L5) and then classified as having type A-E pedicles; type B, C, D, and E pedicles were regarded as abnormal. A subset of these patients, a postoperative CT was performed to evaluate the accuracy of pedicle screw placement. According to the perforation of the medial or lateral pedicle walls by the pedicle screw, the placement of screw was classified by a grade ranging from 0 to 3, and grades 2 and 3 were regarded as misplacement. In total, 3230 pedicles were measured and classified, and the incidence rate of abnormal pedicles in the ND-NF1 group was significantly greater than that of the AIS group (65.9% vs. 61.4%, P = 0.03). The misplacement rate in the ND-NF1 group was significantly greater than that in the AIS group (12.2% vs. 7.4%; P = 0.01), and in terms of the corresponding 1100 pedicles, the incidence rate of abnormal pedicles in the ND-NF1 group was higher than that in the AIS group (71.7% vs. 64.9%; P = 0.02). The incidence rate of abnormal pedicles in patients with ND-NF1 is significantly greater than that of patients with AIS, and it may the reason for the higher misplacement rate of pedicle screws in patients with ND-NF1. Copyright © 2020 Elsevier Inc. All rights reserved.

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出版当年[2020]版：

大类 | 3 区医学

小类 | 4 区临床神经病学 4 区外科

最新[2023]版：

大类 | 4 区医学

小类 | 4 区临床神经病学 4 区外科

第一作者：

第一作者机构： [1]Institute of Spinal Deformity, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, P. R. China.

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通讯机构： [4]Institute of Spinal Deformity, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, P. R. China. [5]Institute of Spinal Deformity, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, P. R. China. [*1]Institute of Spinal Deformity, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, P. R. China. [*2]Institute of Spinal Deformity, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, P. R. China.

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Morphological Differences Between the Pedicles in Nondystrophic Scoliosis Secondary to Neurofibromatosis Type 1 and Those in Adolescent Idiopathic Scoliosis.

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