机构：[1]Key Laboratory of Coarse Cereal Processing (Ministry of Agriculture and Rural Affairs), School of Food and Biological Engineering, Chengdu University, Chengdu, 610106, China.[2]Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu, 610106, China[3]State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China
Polydopamine (PDA) has shown great potentials in biomedical fields due largely to its unique physicochemical properties, including high photothermal transfer efficiency, excellent drug binding capacity, versatile adhesion ability, sensitive pH responsibility and great biocompatibility and biodegradability. These properties confer PDA-based nanoparticles the potentials either as the drug carriers for advanced drug delivery or as the bioactive agents for photothermal therapy, imaging and biosensing. This review aims to provide a comprehensive understanding of PDA, its polymerization mechanisms and the potentials of PDA-based nano-systems in treating various diseases, including cancer, diabetes, inflammation, bacterial infection and Parkinson's disease. In addition, the concerns of PDA in biomedical use are also discussed.
基金：
National Natural Science Foundation of China (81703448 and 81973261), the Applied Basic Research Programs of Sichuan Province Science and Technology Department (2019YJ0663), Project of Sichuan Provincial Science and Technology Department (No.2019YJ0661) and the Research Funding for Talents Developing, West China Hospital of Stomatology, Sichuan University (RCDWJS2020-7).
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2021]版：
大类|2 区工程技术
小类|2 区生物物理2 区物理化学3 区材料科学：生物材料
最新[2023]版：
大类|2 区医学
小类|1 区生物物理2 区物理化学3 区材料科学：生物材料
第一作者：
第一作者机构：[1]Key Laboratory of Coarse Cereal Processing (Ministry of Agriculture and Rural Affairs), School of Food and Biological Engineering, Chengdu University, Chengdu, 610106, China.
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Li Hanmei,Yin Dan,Li Wei,et al.Polydopamine-based nanomaterials and their potentials in advanced drug delivery and therapy.[J].Colloids and surfaces. B, Biointerfaces.2021,199:111502.doi:10.1016/j.colsurfb.2020.111502.
APA：
Li Hanmei,Yin Dan,Li Wei,Tang Qi,Zou Liang&Peng Qiang.(2021).Polydopamine-based nanomaterials and their potentials in advanced drug delivery and therapy..Colloids and surfaces. B, Biointerfaces,199,
MLA：
Li Hanmei,et al."Polydopamine-based nanomaterials and their potentials in advanced drug delivery and therapy.".Colloids and surfaces. B, Biointerfaces 199.(2021):111502
工程技术