机构：[1]Institute of Drug Clinical Trial, Department of Thoracic Oncology of Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China四川大学华西医院[2]Department of Oncology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China[3]Department of Oncology, Second People’s Hospital of Yibin, Yibin, Sichuan, China
Aim: This study aimed to assess the nutritional status of patients with locoregionally advanced nasopharyngeal cancer, for whom intensity-modulated radiotherapy (IMRT) was planned using their pre- or post-induction chemotherapy (IC) nasopharyngeal gross tumor volume. Materials & methods: 212 cases of stage III-IVb nasopharyngeal cancer were randomized into groups A (n = 97) and B (n = 115). IMRT was planned for groups A and B using pre-IC and post-IC images, respectively. Results: There was a significant decrease in the nutritional parameters of group B compared with those of group A during radiotherapy. Multivariate analysis indicated that the T stage and nasopharyngeal gross tumor volume IMRT-planning protocol were prognostic factors of poor nutritional status. Conclusion: Decreasing the IMRT target volume through IC can improve nutritional status.
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2020]版：
大类|4 区医学
小类|4 区肿瘤学
最新[2023]版：
大类|4 区医学
小类|4 区肿瘤学
第一作者：
第一作者机构：[1]Institute of Drug Clinical Trial, Department of Thoracic Oncology of Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China[2]Department of Oncology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China
通讯作者：
推荐引用方式(GB/T 7714)：
Xiang Li,Rong Jin-Feng,Pang Hao-Wen,et al.Nutritional outcomes after radiotherapy target volume reduction for nasopharyngeal cancer: a Phase III trial.[J].Future oncology (London, England).2020,16(9):427-437.doi:10.2217/fon-2019-0785.
APA：
Xiang Li,Rong Jin-Feng,Pang Hao-Wen,He Huai-Lin,Chen Yue...&Wang Yong-Sheng.(2020).Nutritional outcomes after radiotherapy target volume reduction for nasopharyngeal cancer: a Phase III trial..Future oncology (London, England),16,(9)
MLA：
Xiang Li,et al."Nutritional outcomes after radiotherapy target volume reduction for nasopharyngeal cancer: a Phase III trial.".Future oncology (London, England) 16..9(2020):427-437
