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宫颈癌术后IMRT和VMAT放疗技术剂量学研究

Research of postoperative patients with cervical cancer dosimetry of IMRT and VMAT radiotherapy technology

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收录情况: ◇ 统计源期刊 ◇ 北大核心

机构: [1]四川绵阳四〇四医院肿瘤科 [2]四川省肿瘤医院放疗中心 [3]甘肃省肿瘤医院放疗科
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关键词: Cervical cancer Dosimetry Intensity modulated radiotherapy Radiotherapy Volumetric modulated arc therapy

摘要:
OBJECTIVE The incidence of cervical cancer is high in China.Radiotherapy is one of the three major means of treatment of cervical cancer. The papper aimed to discuss the dose distribution characteristics of the postoperative cervical cancer patients treated with static intensity-modulated radiotherapy (IMRT) and rotary volumetric intensity-modulated radiotherapy (VMAT). METHODS Retrospective analysis of 43 patients between 2015-10-31 and 2014-05-01 in Sichuan Cancer Hospital was done.All the patients received adjuvant radiotherapy after surgery for cervical cancer. A fixed-seven-field IMRT and a dual-arc VMAT scheme were designed on the same set of CT images. The prescription dose was 45 Gy/25 F,and the plan statistical result based on the MATLAB platform programming.The dose of the organ, the number of monitor unit and treatment time were compared. RESULTS Small intestinal V30,V20,Bladder V40,Femoral head V20,V30, Pelvic V20,V30,Horsetail Dmax were significantly better in VMAT group than those of the IMRT group (P<0.05).For the pelvis,the average dose of the sacrum was higher than that of the ilium and hip bone (P<0.05). The parameter of dual-arc VMAT including the number of monitor (558±8) MU and treatment time (2.6±0.3) min was significantly better than that of fixed-field IMRT (P<0.05). CONCLUSIONS For patients with cervical cancer after surgery,all of the two kinds can bring a satisfactory conclusion. However, the target dose falling gradient, conformal index and homogeneity index of VMAT plan are better.The treatment time is significantly shortened. From the perspective of dosimetric analysis, VMAT technology has obvious advantages. © 2017, Editorial Board of Chinese Journal of Cancer Prevention and Treatment. All right reserved.

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第一作者机构: [1]四川绵阳四〇四医院肿瘤科
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