机构：[1]Department of Ophthalmology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu City, Sichuan Province, China四川省人民医院[2]Laboratory Animal Institute, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu City, Sichuan Province, China四川省人民医院[3]Department of Neurology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu City, Sichuan Province, China四川省人民医院[4]Sichuan Provincial Key Laboratory for Disease Gene Study, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu City, Sichuan Province, China四川省人民医院[5]Department of Ophthalmology, University of Oklahoma School of Medicine, Oklahoma City, OK, USA[6]Department of Ophthalmology, Dean A. McGee Eye Institute, University of Oklahoma School of Medicine, Oklahoma City, OK, USA[7]Institute for Infocomm Research, Agency for Science, Technology and Research (A*STAR), Singapore
Background: With the ongoing development of surgical procedures and instruments, the safety of optic nerve sheath fenestration (ONSF) has been improved. Objective: Through the past three decades, progress has been made in preventing visual loss from chronic optic nerve swelling in idiopathic intracranial hypertension (IIH), secondary intracranial hypertension and local optic nerve diseases. We now review the updated application of ONSF in those diseases. Methods: The application of ONSF in papilledema due to IIH, secondary intracranial hypertension to cerebral venous sinus occlusion, Cryptococcal meningitis, and intracranial mass or tumors is reviewed. Additionally, the potential benefits of ONSF in local optic neuropathy from optic nerve sheath meningioma, optic nerve drusen, traumatic optic neuropathy and optic nerve/sheath biopsy are also described. Results: Although ONSF has little or no effect on intracranial pressure, it is a safe, relative easy and effective surgical procedure to prevent or reverse visual loss in IIH. When other treatment modalities fail to timely protect vision, ONSF can be useful in protecting visual function or delay visual loss in secondary intracranial hypertension. Conclusion: We recommend that ONSF should be considered as a meaningful alternative or an adjunct therapy to reduce or delay the visual morbidity of these diseases, although the use of ONSF for some of them remains controversial.
基金：
National Basic Research Program of China (973 Program)National Basic Research Program of China [2015CB554100]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81271035/H1205]; High and New Technology Program in Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital of China [2012-6]; Foundation for Returned Personals Studying Abroad in Human Resources Department of Sichuan Province, China
第一作者机构：[1]Department of Ophthalmology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu City, Sichuan Province, China[2]Laboratory Animal Institute, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu City, Sichuan Province, China[*1]Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, No. 32, 1st ring road, 2nd west section, Chengdu City, Sichuan Province 610072, China.
通讯作者：
通讯机构：[1]Department of Ophthalmology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu City, Sichuan Province, China[2]Laboratory Animal Institute, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu City, Sichuan Province, China[4]Sichuan Provincial Key Laboratory for Disease Gene Study, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu City, Sichuan Province, China[5]Department of Ophthalmology, University of Oklahoma School of Medicine, Oklahoma City, OK, USA[6]Department of Ophthalmology, Dean A. McGee Eye Institute, University of Oklahoma School of Medicine, Oklahoma City, OK, USA[*1]Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, No. 32, 1st ring road, 2nd west section, Chengdu City, Sichuan Province 610072, China.[*2]Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, No. 32, 1st ring road, 2nd west section, Chengdu City, Sichuan Province 610072, China.[*3]Farris, Department of Ophthalmology, Dean A. McGee Eye Institute, University of Oklahoma Health Sciences Center, 608 Stanton L. Young Boulevard, Oklahoma City, OK 73104, USA.
推荐引用方式(GB/T 7714)：
Chen Hui,Zhang Qian,Tan Song,et al.Update on the application of optic nerve sheath fenestration[J].RESTORATIVE NEUROLOGY AND NEUROSCIENCE.2017,35(3):275-286.doi:10.3233/RNN-160693.
APA：
Chen, Hui,Zhang, Qian,Tan, Song,Fu, Huazhu,Farris, Bradley K.&Yang, Zhenglin.(2017).Update on the application of optic nerve sheath fenestration.RESTORATIVE NEUROLOGY AND NEUROSCIENCE,35,(3)
MLA：
Chen, Hui,et al."Update on the application of optic nerve sheath fenestration".RESTORATIVE NEUROLOGY AND NEUROSCIENCE 35..3(2017):275-286
