A Biocompatible Colorimetric Triphenylamine- Dicyanovinyl Conjugated Fluorescent Probe for Selective and Sensitive Detection of Cyanide Ion in Aqueous Media and Living Cells.
机构：[1]Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China[2]University of Chinese Academy of Sciences, Beijing 100049, China[3]Cancer Center,West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu 610041, China
A colorimetric and turn-on fluorescent probe 1 bearing triphenylamine-thiophene and dicyanovinyl groups has been synthesized and used to detect cyanide anion via a nucleophilic addition reaction. Probe 1 exhibited prominent selectivity and sensitivity towards CN- in aqueous media, even in the presence of other anions such as S2-, HS-, SO₃2-, S₂O₃2-, S₂O₈2-, I-, Br-, Cl-, F-, NO₂-, N₃-, SO₄2-, SCN-, HCO₃-, CO₃2- and AcO-. Moreover, a low detection limit (LOD, 51 nM) was observed. In addition, good cell membrane permeability and low cytotoxicity to HeLa cells were also observed, suggesting its promising potential in bio-imaging.
基金：
Basic Research Project of Sichuan Province [2014JY0205]
语种：
外文
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2017]版：
大类|3 区工程技术
小类|2 区仪器仪表3 区分析化学4 区电化学
最新[2023]版：
大类|3 区综合性期刊
小类|2 区分析化学3 区工程：电子与电气3 区仪器仪表
第一作者：
第一作者机构：[1]Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China[2]University of Chinese Academy of Sciences, Beijing 100049, China
通讯作者：
通讯机构：[1]Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China[3]Cancer Center,West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu 610041, China
推荐引用方式(GB/T 7714)：
Zheng Zi-Hua,Li Zhi-Ke,Song Lin-Jiang,et al.A Biocompatible Colorimetric Triphenylamine- Dicyanovinyl Conjugated Fluorescent Probe for Selective and Sensitive Detection of Cyanide Ion in Aqueous Media and Living Cells.[J].SENSORS.2017,17(2):-.doi:10.3390/s17020405.
APA：
Zheng Zi-Hua,Li Zhi-Ke,Song Lin-Jiang,Wang Qi-Wei,Huang Qing-Fei&Yang Li.(2017).A Biocompatible Colorimetric Triphenylamine- Dicyanovinyl Conjugated Fluorescent Probe for Selective and Sensitive Detection of Cyanide Ion in Aqueous Media and Living Cells..SENSORS,17,(2)
MLA：
Zheng Zi-Hua,et al."A Biocompatible Colorimetric Triphenylamine- Dicyanovinyl Conjugated Fluorescent Probe for Selective and Sensitive Detection of Cyanide Ion in Aqueous Media and Living Cells.".SENSORS 17..2(2017):-
