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Comparative mitochondrial genome and phylogenetic analysis of malaria mosquitoes Anopheles hyrcanus and Anopheles messeae

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机构: [1]1Integrated Laboratory of Pathogenic Biology, College of Preclinical Medicine, Dali University, Dali, Yunnan, China. [2]Yunnan Institute of Parasitic Disease, Puer, Yunnan, China. [3]School of Public Health, Dali University, Dali, Yunnan, China. [4]Dali Bai Autonomous Prefecture People’s Hospital Ophthalmology, No.35 Renmin South Road, Dali, Yunnan, China. [5]Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention, Urumqi, Xinjiang, China. [6]Department of Gastroenterology, Clinical Medical College and the First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, China. [7]Key Laboratory of Gastrointestinal Tumors and Microenvironment, Sichuan Provincial Universities, Chengdu, Sichuan, China. [8]Department of Infection, The First Affiliated Hospital of Dali University, Dali, Yunnan, China. [9]the Key Laboratory of Infectious Diseases of Yunnan Provincial Education Department, Dali, Yunnan, China.
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关键词: Mosquitoes Mitochondrial genomes Anopheles hyrcanus Anopheles Messeae Phylogenetic

摘要:
Anopheles mosquitoes serve as a significant vector for the transmission of malaria and arboviruses holding great medical importance, but their phylogenetic relationships have not yet been clearly elucidated. This study was the first to sequence and analyze the mitochondrial genomic features of An. hyrcanus and An. messeae, and to incorporate them into a phylogenetic analysis with 102 other species within the genus Anopheles. Both genomes contain 37 genes, including 22 tRNAs, 13 protein-coding genes and 2 rRNAs, as well as one control region. The genome characteristics, codon usage, and tRNA secondary structure of the two species align with those observed in mitochondrial genomes of other mosquito species. Phylogenetic analysis revealed that the relationship among six subgenera was Lophopodomyia + ((Kerteszia + Stethomyia) + ((Cellia + Anopheles) + Nyssorhynchus)), providing strong support for their monophyly. Nevertheless, the phylogenetic relationships within subgenus Cellia were inconsistent with previous findings. The findings of this study will enrich the biological information repository for Anopheles mosquitoes, lay the foundation for further research on systematic classification, and hold significant implications for guiding the research, prevention and control of mosquito-borne diseases.© 2025. The Author(s).

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出版当年[2025]版:
大类 | 3 区 综合性期刊
小类 | 3 区 综合性期刊
最新[2025]版:
大类 | 3 区 综合性期刊
小类 | 3 区 综合性期刊
第一作者:
第一作者机构: [1]1Integrated Laboratory of Pathogenic Biology, College of Preclinical Medicine, Dali University, Dali, Yunnan, China.
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通讯作者:
通讯机构: [6]Department of Gastroenterology, Clinical Medical College and the First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, China. [7]Key Laboratory of Gastrointestinal Tumors and Microenvironment, Sichuan Provincial Universities, Chengdu, Sichuan, China. [8]Department of Infection, The First Affiliated Hospital of Dali University, Dali, Yunnan, China. [9]the Key Laboratory of Infectious Diseases of Yunnan Provincial Education Department, Dali, Yunnan, China.
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