个人中心| | 帮助
高级检索
当前位置： 首页 > 详情页

Prevalence and prognostic significance of interstitial lung abnormalities in lung cancer: A meta-analysis

| 认领 | 导出 | |

文献详情

资源类型：
Pubmed体系：
作者：
Yang Ruiyuan[1,2] * ; Wang Haoyu[1,2] * ; Liu Dan[1,2] ; Li Weimin[1,2,3,4,5,6] ;
机构： [1]Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041 Sichuan, China [2]State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Chengdu 610041 Sichuan, China [3]Institute of Respiratory Health, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041 Sichuan, China [4]Precision Medicine Center, Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu 610041 Sichuan, China [5]The Research Units of West China, Chinese Academy of Medical Sciences, West China Hospital, Chengdu 610041 Sichuan, China [6]Institute of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, Sichuan, China
出处：
DOI： 10.1016/j.lungcan.2025.108458
ISSN：

关键词： Interstitial lung abnormalities Lung cancer Prevalence Prognosis

摘要：
With the increasing popularity of lung cancer screening (LCS), substantial incidental findings in CT have been identified, particularly interstitial lung abnormalities (ILAs). ILAs have been reported in several studies on lung cancer. However, the relationship between ILAs and lung cancer has not been comprehensively investigated.To explore the occurrence of ILAs in lung cancer and its effect on the prognosis of lung cancer.PubMed, Web of Science, Embase, and Scopus were searched for relevant publications. Pooled prevalence, odds ratios (ORs), and hazard ratios (HRs) were utilized to assess the prevalence of ILAs and their association with clinical outcomes in lung cancer. This study was performed in line with PRISMA and was registered at PROSPERO.Twenty-four studies involving 7859 patients were identified. The prevalence of ILAs in lung cancer was 17 % (unadjusted, 95 % confidence interval [CI]: 13 %-21 %), and the prevalence after correction was 9 % (95 %CI: 6 %-13 %), while reticulation and ground glass attenuation are the main imaging patterns. ILAs are also associated with shortened overall survival in lung cancer (HR = 2.01, 95 %CI: 1.71-2.36) and increased risk of checkpoint inhibitor pneumonia (OR = 2.86, 95 %CI: 1.42-5.75) and radiation pneumonitis (OR = 2.98, 95 %CI: 1.39-6.38).ILAs are unignorable and associated with poor outcomes of treatment and survival in patients with lung cancer. Therefore, clinicians should focus on these patients with ILAs during lung cancer diagnosis and treatment. Standardized identification and reporting of ILAs in chest CT examinations are also crucial.Copyright © 2025 The Author(s). Published by Elsevier B.V. All rights reserved.

基金：
Financial support and sponsorship: This work was supported by the National Natural Science Foundation of China (grant number 92159302), the Science and Technology Project of Sichuan (grant number 2022ZDZX0018), State Key Laboratory of Respiratory Health and Multimorbidity, State Key Laboratory Special Fund (grant number 2060204) and the project for disciplines of excellence, West China Hospital, Sichuan University (grant number ZYGD22009) to Weimin Li.
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2025]版：
大类 | 2 区 医学
小类 | 3 区 肿瘤学 3 区 呼吸系统
最新[2025]版：
大类 | 2 区 医学
小类 | 3 区 肿瘤学 3 区 呼吸系统
第一作者：
第一作者机构： [1]Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041 Sichuan, China [2]State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Chengdu 610041 Sichuan, China
共同第一作者：
通讯作者：
通讯机构： [1]Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041 Sichuan, China [2]State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Chengdu 610041 Sichuan, China [3]Institute of Respiratory Health, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041 Sichuan, China [4]Precision Medicine Center, Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu 610041 Sichuan, China [5]The Research Units of West China, Chinese Academy of Medical Sciences, West China Hospital, Chengdu 610041 Sichuan, China [6]Institute of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, Sichuan, China
推荐引用方式(GB/T 7714)：
Yang Ruiyuan,Wang Haoyu,Liu Dan,et al.Prevalence and prognostic significance of interstitial lung abnormalities in lung cancer: A meta-analysis[J].Lung Cancer (Amsterdam, Netherlands).2025,205:108458.doi:10.1016/j.lungcan.2025.108458.
APA：
Yang Ruiyuan,Wang Haoyu,Liu Dan&Li Weimin.(2025).Prevalence and prognostic significance of interstitial lung abnormalities in lung cancer: A meta-analysis.Lung Cancer (Amsterdam, Netherlands),205,
MLA：
Yang Ruiyuan,et al."Prevalence and prognostic significance of interstitial lung abnormalities in lung cancer: A meta-analysis".Lung Cancer (Amsterdam, Netherlands) 205.(2025):108458

相关文献

[1]Sex Disparities in the Clinical Characteristics, Synchronous Distant Metastasis Occurrence and Prognosis: A Pan-cancer Analysis [2]Burden of Lung Cancer in China, 1990-2019: Findings from the Global Burden of Disease Study 2019 [3]Prevalence and associated factors of cognitive frailty in older patients with lung cancer undergoing chemotherapy: a cross-sectional study [4]Erratum to Prevalence and clinical significance of pathogenic germline BRCA1/2 mutations in Chinese non-small cell lung cancer patients. [5]Prevalence and clinical significance of pathogenic germline BRCA1/2 mutations in Chinese non-small cell lung cancer patients [6]Clinical and oncologic findings of extraprostatic extension on needle biopsy in de novo metastatic prostate cancer. [7]Sarcopenia prevalence in patients with cancer and association with adverse prognosis: A nationwide survey on common cancers [8]Surgical treatment of small-cell lung cancer: long-term prognosis and patterns of adjuvant therapy [9]Factors That Improve Chest Computed Tomography-Defined Sarcopenia Prognosis in Advanced Non-Small Cell Lung Cancer. [10]Lymphocyte percentage as a valuable predictor of prognosis in lung cancer.

资源点击量：65780 今日访问量：0 总访问量：5151 更新日期：2025-12-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 四川省肿瘤医院 技术支持：重庆聚合科技有限公司 地址：成都市人民南路四段55号