详情页 - 四川省肿瘤医院知识库

当前位置：首页 > 详情页

Polysaccharides as a promising platform for the treatment of spinal cord injury: A review

文献详情

资源类型：

Pubmed体系：

作者：

机构： [1]Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China [2]Department of Neurosurgery and Institute of Neurosurgery, West China Hospital, Sichuan University, Chengdu 610041, China [3]Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu 610041, China

出处：

DOI：

ISSN：

关键词： Spinal cord injury Polysaccharides Drug delivery systems Anti-inflammatory Anti-apoptosis Axonal regeneration

摘要：

Spinal cord injury is incurable and often results in irreversible damage to motor function and autonomic sensory abilities. To enhance the effectiveness of therapeutic substances such as cells, growth factors, drugs, and nucleic acids for treating spinal cord injuries, as well as to reduce the toxic side effects of chemical reagents, polysaccharides have been gained attention due to their immunomodulatory properties and the biocompatibility and biodegradability of polysaccharide scaffolds. Polysaccharides hold potential as drug delivery systems in treating spinal cord injuries. This article aims to present an extensive evaluation of the potential applications of polysaccharide materials in scaffold construction, drug delivery, and immunomodulation over the past five years so that offering new directions and opportunities for the treatment of spinal cord injuries.Copyright © 2023. Published by Elsevier Ltd.

语种：

PubmedID：

中科院(CAS)分区：

出版当年[2023]版：

大类 | 1 区

化学

小类 | 1 区应用化学 1 区有机化学 1 区高分子科学

最新[2023]版：

大类 | 1 区

化学

小类 | 1 区应用化学 1 区有机化学 1 区高分子科学

第一作者：

第一作者机构： [1]Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China

共同第一作者：

通讯作者：

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Polysaccharide-based nanomedicines for cancer immunotherapy: A review. [2]Preparation and application of pH-responsive drug delivery systems. [3]GelMA-MXene hydrogel nerve conduits with microgrooves for spinal cord injury repair [4]Intraoperative contrast-enhanced ultrasonography for microcirculatory evaluation in rhesus monkey with spinal cord injury [5]外泌体作为药物传递系统的前景及挑战 [6]Effective improvement of the neuroprotective activity after spinal cord injury by synergistic effect of glucocorticoid with biodegradable amphipathic nanomicelles. [7]Antibody-based drug delivery systems for cancer therapy: Mechanisms, challenges, and prospects. [8]外泌体作为药物传递系统的前景及挑战 [9]Advances in Drug Delivery Systems for the Treatment of Acute Myeloid Leukemia [10]PLGA-Based Drug Delivery Systems for Remotely Triggered Cancer Therapeutic and Diagnostic Applications.