Determining the safety and effectiveness of percutaneous nephrolithotomy and retrograde intrarenal surgery in treating nephrolithiasis in patients with solitary kidneys
机构：[1]Nanchong Central Hospital, Department of Urology, The Second Clinical College, North Sichuan Medical College (University), Nanchong, 637000, Sichuan, China.[2]Department of Urology, The Second Hospital of Lanzhou University Medical School, LanzhouGansu, 730000, China.[3]Institute of Urology, Clinical Laboratory, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen, 518000, China.深圳市罗湖区人民医院深圳医学信息中心[4]South China Hospital, Health Science Center, The Affiliated Hospital of Shenzhen University, Shenzhen, 518000, China.[5]Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.[6]Institute of Urology, Department of Urology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. hxcaodehong@163.com.四川大学华西医院[7]State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, Sichuan, China四川大学华西医院
We performed a meta-analysis to compare the safety and effectiveness of percutaneous nephrolithotomy (PCNL) and retrograde
intrarenal surgery (RIRS) in treating nephrolithiasis ≥ 2 cm in patients with solitary kidneys. This systematic review
was registered on PROSPERO (registration ID: CRD42021270519). The search time was set from the establishment of the
databases until April 30, 2021. A systematic search was performed in the PubMed, MEDLINE, Web of Science, Scopus,
China National Knowledge Infrastructure (CNKI), Cochrane Library, and Embase databases. Stata 16 was used to perform
the statistical analysis of the extracted data. After screening using strict inclusion and exclusion criteria, five studies with a
total of 474 patients were included in the final meta-analysis. According to the literature quality assessment scale statistics,
the five studies included were of high quality. The results of the meta-analysis showed that RIRS had lesser hemoglobin loss
(HL), shorter length of hospital stay (LOS), lower initial (OR = 3.39, 95% CI [1.97, 5.83], P = 0.02) and final stone-free rates
(OR = 2.24, 95% CI [1.24, 4.06], P = 0.03), but a higher incidence of grade III-IV complications (OR = 0.29, 95% CI [0.08,
0.97], P = 0.04) than PCNL. The difference between the two surgical methods was not statistically significant in terms of
operation time (OT), grade I–II complication rate, and total complication rate. For nephrolithiasis ≥ 2 cm in patients with a
solitary kidney, RIRS has the advantage of less HL and shorter LOS, while PCNL benefits from its higher SFR (both initial
and final). Both RIRS and PCNL are effective treatments for nephrolithiasis in patients with a solitary kidney, and clinicians
should choose the most appropriate option to achieve the best treatment outcome, taking into account the patient's underlying
conditions and medical conditions.
基金：
Sichuan Province Science
and Technology Planning Project under grant number 2020YFS0320
and the Sichuan Provincial Health Committee Research Project under
grant number 20PJ305.
第一作者机构：[1]Nanchong Central Hospital, Department of Urology, The Second Clinical College, North Sichuan Medical College (University), Nanchong, 637000, Sichuan, China.[2]Department of Urology, The Second Hospital of Lanzhou University Medical School, LanzhouGansu, 730000, China.[3]Institute of Urology, Clinical Laboratory, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen, 518000, China.[4]South China Hospital, Health Science Center, The Affiliated Hospital of Shenzhen University, Shenzhen, 518000, China.
共同第一作者：
通讯作者：
通讯机构：[6]Institute of Urology, Department of Urology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. hxcaodehong@163.com.[7]State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, Sichuan, China
推荐引用方式(GB/T 7714)：
Peng Lei,Meng Chunyang,Xia Zhongyou,et al.Determining the safety and effectiveness of percutaneous nephrolithotomy and retrograde intrarenal surgery in treating nephrolithiasis in patients with solitary kidneys[J].UROLITHIASIS.2022,51(1):doi:10.1007/s00240-022-01386-3.
APA：
Peng Lei,Meng Chunyang,Xia Zhongyou,Liang Rui,Gan Lijian...&Li Yunxiang.(2022).Determining the safety and effectiveness of percutaneous nephrolithotomy and retrograde intrarenal surgery in treating nephrolithiasis in patients with solitary kidneys.UROLITHIASIS,51,(1)
MLA：
Peng Lei,et al."Determining the safety and effectiveness of percutaneous nephrolithotomy and retrograde intrarenal surgery in treating nephrolithiasis in patients with solitary kidneys".UROLITHIASIS 51..1(2022)
