机构：[1]School of Materials Science and Engineering, Southeast University, Nanjing 211189, China.[2]School of Materials and Physics, China University of Mining and Technology, Xuzhou 221116, China.[3]School of Mechanical and Aerospace Engineering, Queen's University, Belfast BT9 5AH, UK.[4]Laboratory of Stem Cell and Tissue Engineering, Orthopedic Research Institute, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu 610041, China.四川大学华西医院
In this work, a facile direct current atmospheric pressure micro-plasma (APM) technology was deployed for the synthesis of functional gold nanoparticle/chitosan (AuNP/CS) nanocomposites for the first time. Different experimental parameters, such as metal salt precursor concentration and chitosan viscosity, have been investigated to understand their effects on the resulting nanocomposite structures and properties. The nanocomposites were fully characterized using a wide range of material characterization techniques such as UV-vis, transmission electron microscope (TEM), Fourier transform infrared (FTIR) spectra and X-ray photoelectron spectroscopy (XPS) analyses. Potential reaction pathways have been proposed for the nanocomposite synthesis process. Finally, potential of the synthesized nanocomposites towards photothermal conversion and bacteria eradiation applications has been demonstrated. The results show that APM is a facile, rapid and versatile technique for the synthesis of AuNP/CS functional nanocomposites. Through this work, a more in-depth understanding of the multi-phase system (consisting of gas, plasma, liquid and solid) has been established and such understanding could shine a light on the future design and fabrication of new functional nanocomposites deploying the APM technique.
基金：
National Natural Science Foundation of China (52001324;
32071331), Natural Science Foundation of Jiangsu Province (BK20200643), Engineering and Physical
Sciences Research Council for funding support (EP/P00394X/1), China Postdoctoral Science Foundation (2020M671641), and Fundamental Research Funds for the central University of Ministry of
Education of China (2020QN34).
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2022]版：
大类|2 区医学
小类|2 区药学
最新[2023]版：
大类|3 区医学
小类|2 区药学
第一作者：
第一作者机构：[1]School of Materials Science and Engineering, Southeast University, Nanjing 211189, China.[2]School of Materials and Physics, China University of Mining and Technology, Xuzhou 221116, China.
通讯作者：
推荐引用方式(GB/T 7714)：
Guo Zhijun,Sun Dan,Zhou Xian,et al.AuNP/Chitosan Nanocomposites Synthesized through Plasma Induced Liquid Chemistry and Their Applications in Photothermal Induced Bacteria Eradication[J].Pharmaceutics.2022,14(10):doi:10.3390/pharmaceutics14102147.
APA：
Guo Zhijun,Sun Dan,Zhou Xian,Xu Huan,Huang Yizhou...&Shen Baolong.(2022).AuNP/Chitosan Nanocomposites Synthesized through Plasma Induced Liquid Chemistry and Their Applications in Photothermal Induced Bacteria Eradication.Pharmaceutics,14,(10)
MLA：
Guo Zhijun,et al."AuNP/Chitosan Nanocomposites Synthesized through Plasma Induced Liquid Chemistry and Their Applications in Photothermal Induced Bacteria Eradication".Pharmaceutics 14..10(2022)
