机构：[1]Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.[2]Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.[3]Organ transplantation center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Kidneys from pDDs are increasingly used to narrow the huge gap between incremental demand and static supply. However, there is still controversy on the clinical outcome of SKT from pDDs. We conducted a retrospective cohort study of 452 adult recipients in our center between March 2012 and February 2017. Outcomes of 3 groups, transplants with organs from pDDs (n=50), aDDs (n=207), and LDs (n=195), were compared. The mean age and weight of pDDs were 8.98 years (range 8 months-17 years) and 30.05 kg (range 8.2-55 kg), respectively. There was no difference in 1-year (96.0%, 98.1%, and 99.0%, respectively, P=.277) and 3-year patient survival (96.0%, 98.1%, and 99.0%, respectively, P=.277) or in 1-year (96.0%, 96.6%, and 98.5%, P=.307) and 3-year (96.0%, 96.6% and 97.9%, P=.437) graft survival. SCr, eGFR, and allograft size were similar among the 3 groups at 6th month post-transplant and thereafter. Incidence of DGF was higher in patients of the aDD group than those in the pDD group (22.7% vs 10.0%, P<.001), but there was no difference in AR and infection. SKT from pDDs to adult recipients is effective and safe with acceptable outcomes, and it will be a promising expansion to the donor pool.
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2018]版：
大类|4 区医学
小类|4 区儿科4 区移植
最新[2023]版：
大类|4 区医学
小类|4 区儿科4 区移植
第一作者：
第一作者机构：[1]Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.[2]Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.[3]Organ transplantation center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
通讯作者：
通讯机构：[1]Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.[2]Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.[3]Organ transplantation center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
推荐引用方式(GB/T 7714)：
蒋亚梅,宋涂润,邱阳,et al.Outcomes of single kidney transplantation from pediatric donors: A single-center experience[J].Pediatric Transplantation.2018,22(5):doi:10.1111/petr.13196.
APA：
蒋亚梅,宋涂润,邱阳,刘金鹏,王志灵...&林涛.(2018).Outcomes of single kidney transplantation from pediatric donors: A single-center experience.Pediatric Transplantation,22,(5)
MLA：
蒋亚梅,et al."Outcomes of single kidney transplantation from pediatric donors: A single-center experience".Pediatric Transplantation 22..5(2018)
