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Exosomes as Drug Carriers in Anti-Cancer Therapy.

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收录情况： ◇ SCIE ◇ 预警期刊

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机构： [1]Lung Cancer Center, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu, China. [2]School of Medicine, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, University of Electronic Science and Technology of China, Chengdu, China.

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关键词： exosomes drug delivery cancer therapy targetability engineering

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Over the years, there has been a high demand for developing new safe and effective drug carriers for cancer therapy. Emerging studies have indicated that exosomes can serve as potent therapeutic carriers since they offer low immunogenicity, high stability, innate and acquired targetability, and the stimulation of anti-cancer immune responses. Yet, the development of exosome-based drug delivery systems remains challenging due to their heterogeneity, low yield, and limited drug loading efficiency. Herein, we summarized the current application of exosomes derived from different cells as drug carriers in anti-cancer therapy in vitro and in vivo. We also discussed the challenges and prospects of exosome-based drug delivery systems in cancer therapy.Copyright © 2022 Chen, Wang, Zhu, Xu, Liu, Li, Zhou and Luo.

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出版当年[2022]版：

大类 | 2 区生物学

小类 | 2 区发育生物学 3 区细胞生物学

最新[2023]版：

大类 | 2 区生物学

小类 | 2 区发育生物学 3 区细胞生物学

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出版当年[2022]版：

Q1 DEVELOPMENTAL BIOLOGY Q2 CELL BIOLOGY

最新[2023]版：

Q1 DEVELOPMENTAL BIOLOGY Q2 CELL BIOLOGY

影响因子： 4.6 最新[2023版] 5.2 最新五年平均 5.5 出版当年[2022版] 5.8 出版当年五年平均 6.081 出版前一年[2021版] 4.6 出版后一年[2023版]

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第一作者机构： [1]Lung Cancer Center, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu, China.

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