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Relationship between exosomes and cancer: formation, diagnosis, and treatment

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机构: [1]Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China. [2]Sichuan university, West China Hospital of Sichuan University, Chengdu 610041, China. [3]Health Management Center, General Practice Medical Center, West China Hospital, Sichuan University, Chengdu, China. [4]State Key Laboratory of Respiratory Health and Multimorbidity, China. [5]Research Laboratory for Prediction and Evaluation of Chronic Diseases in the Elderly, National Clinical Research Center for Geriatric Diseases, China. [6]General Practice Research Institute, West China Hospital, Sichuan University, Chengdu, China.
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关键词: Exosome Cancer Cancer diagnosis Biomarker Immunotherapy Drug delivery

摘要:
Exosomes are a member of extracellular vesicles. However, their biological characteristics differ from those of other vesicles, and recently, their powerful functions as information molecules, biomarkers, and carriers have been demonstrated. Malignancies are the leading cause of high morbidity and mortality worldwide. The cure rate of malignancies can be improved by improving early screening rates and therapy. Moreover, a close correlation between exosomes and malignancies has been observed. An in-depth study of exosomes can provide new methods for diagnosing and treating tumors. Therefore, this study aimed to review, sort, and summarize such achievements, and present ideas and opinions on the application of exosomes in tumor treatment.© The author(s).

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最新[2023]版:
大类 | 2 区 生物学
小类 | 2 区 生化与分子生物学
第一作者:
第一作者机构: [1]Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
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通讯作者:
通讯机构: [3]Health Management Center, General Practice Medical Center, West China Hospital, Sichuan University, Chengdu, China. [4]State Key Laboratory of Respiratory Health and Multimorbidity, China. [5]Research Laboratory for Prediction and Evaluation of Chronic Diseases in the Elderly, National Clinical Research Center for Geriatric Diseases, China. [6]General Practice Research Institute, West China Hospital, Sichuan University, Chengdu, China.
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