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Fertility preservation among young breast cancer patients: A single-center experience in China

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机构: [1]Department of Reproductive Medicine, Chengdu Jinjiang Maternal and Child Health Hospital, Chengdu, 610041, Sichuan, China [2]Department of Gynaecology and Obstetrics, West China Second University Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Sichuan University, Chengdu, 610041, Sichuan, China [3]Department of Breast Surgery, Sichuan Cancer Hospital, Chengdu, 610041, Sichuan, China
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关键词: Breast cancer Cryopreservation Oocytes Embryos Fertility preservation

摘要:
Objective: This study aims to investigate the status of fertility preservation (FP) in young breast cancer patients. Materials and methods: A clinical database of six women with breast cancer who wished to undergo FP before starting chemotherapy were analyzed between January 2018 and December 2019 in our hospital. Among the six women, three were unmarried and three were married. Results: Three patients chose oocyte preservation and obtained 23, 7, and 17 MII oocytes, respectively. One patient chose embryo freezing, and three embryos were frozen. Fertility preservation failed for two patients, one of whom had premature ovulation, while the other patient abandoned egg retrieval on the human chorionic gonadotropin (HCG) day. Conclusion: The present results indicate that oocyte and embryo cryopreservation are effective optional methods for young breast cancer patients. However, a lack of knowledge, the urgency of cancer treat-ment, and financial constraints are causes for a low access rate regarding this process. (c) 2021 Taiwan Association of Obstetrics & Gynecology. Publishing services by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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基金编号: 2018JY0295

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出版当年[2021]版:
大类 | 4 区 医学
小类 | 4 区 妇产科学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 妇产科学
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出版当年[2021]版:
Q4 OBSTETRICS & GYNECOLOGY
最新[2023]版:
Q2 OBSTETRICS & GYNECOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2021版] 出版当年五年平均 出版前一年[2020版] 出版后一年[2022版]

第一作者:
第一作者机构: [1]Department of Reproductive Medicine, Chengdu Jinjiang Maternal and Child Health Hospital, Chengdu, 610041, Sichuan, China [2]Department of Gynaecology and Obstetrics, West China Second University Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Sichuan University, Chengdu, 610041, Sichuan, China
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通讯作者:
通讯机构: [3]Department of Breast Surgery, Sichuan Cancer Hospital, Chengdu, 610041, Sichuan, China [*1]Department of Breast Surgery, Sichuan Cancer Hospital, No. 55 of section 4, South Renmin Road, Wuhou District, Chengdu, 610041, China.
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