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Functional gadolinium-based nanoscale systems for cancer theranostics.

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机构： [a]Huaxi MR Research Center (HMRRC), Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China [b]Amgen Bioprocessing Centre, Keck Graduate Institute, Claremont, CA 91711, USA

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关键词： Gadolinium Nanomaterials Cancer theranostics Cancer imaging Anticancer efficacy

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Cancer theranostics is a new strategy for combating cancer that integrates cancer imaging and treatment through theranostic agents to provide an efficient and safe way to improve cancer prognosis. Design and synthesis of these cancer theranostic agents are crucial since these agents are required to be biocompatible, tumor-specific, imaging distinguishable and therapeutically efficacious. In this regard, several types of gadolinium (Gd)-based nanomaterials have been introduced to combine different therapeutic agents with Gd to enhance the efficacy of therapeutic agents. At the same time, the entire treatment procedure could be monitored via imaging tools due to incorporation of Gd ions, Gd chelates and Gd/other imaging probes in the theranostic agents. This review aims to overview recent advances in the Gd-based nanomaterials for cancer theranostics and perspectives for Gd nanomaterial-based cancer theranostics are provided. Copyright © 2020 Elsevier B.V. All rights reserved.

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出版当年[2021]版：

大类 | 1 区

医学

小类 | 1 区药学 2 区化学综合

最新[2023]版：

大类 | 1 区

医学

小类 | 1 区化学：综合 1 区药学

第一作者：

第一作者机构： [a]Huaxi MR Research Center (HMRRC), Department of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China

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