机构：[1]Department of Clinical Pharmacy, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, No. 55, Section 4, South Renmin Road, Chengdu 610041, Sichuan, China临床药学部临床药学部四川省人民医院四川省肿瘤医院[2]Personalized Drug Therapy Key Laboratory of Sichuan Province, Chengdu, China[3]Department of Gynecology and Obstetrics, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, Chengdu, China四川省人民医院
Cancer is a serious public health problem in the world and the prevention and control of cancer has become one of the health strategies of governments around the world. According to the data of the International Agency for Research on Cancer (IARC), about 8 million people die of cancer every year in the world. With the continuous progress of medical technology, there are many methods to treat cancer at present. However, many treatment methods have achieved different therapeutic effects, some of them have obvious toxic and side effects. Therefore, it is necessary to study simpler and more effective new therapies for alleviating pain and prolonging lifetime of patients. In this view, we focus on the application progress of CRISPR system in some major cancers and its potential in cancer treatments.
基金：
We thank the National Key Specialty Construction
Project of Clinical Pharmacy (Grant no.30305030698), the Science and
Technology Program of Sichuan Province (Grant nos. 2009SZ0226,
2014FZ0103, 2015JQO027, 2015ZR0160, 20ZDYF1490, and
20CXTD0043), the Health Department of Sichuan Province (Grant
nos. 100491, 120111, 20PJ110, and 17ZD038), Sichuan Cancer Hospital
(Grant no. YB2019001), Chengdu City Science and Technology
Project (Grant no.11PPYB010SF-289), and the Young Scholars
Foundation of Sichuan Provincial People’s Hospital (Grant nos.
30305030606 and 30305030859). The Cadre Health Care Research
Project of Sichuan Province (Grant no. 2019-801), and Zambon Pharmaceutical
Scientific Research Foundation of the Chengdu Pharmaceutical
Association (Grant no. 201905).
第一作者机构：[1]Department of Clinical Pharmacy, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, No. 55, Section 4, South Renmin Road, Chengdu 610041, Sichuan, China[2]Personalized Drug Therapy Key Laboratory of Sichuan Province, Chengdu, China
共同第一作者：
通讯作者：
通讯机构：[1]Department of Clinical Pharmacy, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, No. 55, Section 4, South Renmin Road, Chengdu 610041, Sichuan, China[2]Personalized Drug Therapy Key Laboratory of Sichuan Province, Chengdu, China
推荐引用方式(GB/T 7714)：
Z. Liu,Z. Liao,Y. Chen,et al.Research on CRISPR/system in major cancers and its potential in cancer treatments[J].CLINICAL & TRANSLATIONAL ONCOLOGY.2021,23(3):425-433.doi:10.1007/s12094-020-02450-3.
APA：
Z. Liu,Z. Liao,Y. Chen,L. Zhou,W. Huangting&H. Xiao.(2021).Research on CRISPR/system in major cancers and its potential in cancer treatments.CLINICAL & TRANSLATIONAL ONCOLOGY,23,(3)
MLA：
Z. Liu,et al."Research on CRISPR/system in major cancers and its potential in cancer treatments".CLINICAL & TRANSLATIONAL ONCOLOGY 23..3(2021):425-433
