机构：[1]Department of Radiation Oncology, Sichuan Cancer Hospital, Chengdu, Sichuan, China四川省肿瘤医院[2]Department of Radiation Oncology, Monmouth Medical Center, Long Branch, NJ, USA
The goal of this study was to evaluate the use of multi-criteria optimization (MCO) in the planning and optimization of intensity-modulated radiotherapy (IMRT). Twenty (20) IMRT patients (ten (10) with prostate cancer and ten (10) with lung cancer) were randomly selected. The treatment plans for these patients were designed using direct machine parameter optimization (DMPO). Based on these plans, new plans were designed using multi-criteria optimization (MCO), keeping the optimization objectives and constraints unchanged. Comparisons were made between the new plans, which were based on MCO and DMPO, including the dose distribution, dose volume histogram (DVH), the optimization time and the number of monitor units (MUs). The plan designed using both optimization approaches satisfied all clinical requirements. For similar or better target coverage, the rectum, bladder and small bowel were better protected using MCO than when using DMPO. Additionally, MCO reduced the time for optimization by 58% on average, whereas the MUs increased the time for optimization by 32% on average for prostate cancer. For lung cancer cases, the entire lung, heart and spinal cord were better protected using MCO compared to DMPO. Similarly, MCO reduced the time for optimization by 59% on average, whereas the MUs increased the time for optimization by 11% on average. Compared to DMPO, MCO reduces the dose of the organs at risk (OAR) and shortens the time required for optimization.
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2017]版：
大类|4 区医学
小类|4 区工程：生物医学4 区卫生保健与服务
最新[2023]版：
大类|4 区医学
小类|4 区工程：生物医学4 区卫生保健与服务
JCR分区：
出版当年[2017]版：
Q4HEALTH CARE SCIENCES & SERVICESQ4ENGINEERING, BIOMEDICAL
最新[2023]版：
Q3HEALTH CARE SCIENCES & SERVICESQ4ENGINEERING, BIOMEDICAL
第一作者机构：[1]Department of Radiation Oncology, Sichuan Cancer Hospital, Chengdu, Sichuan, China
通讯作者：
通讯机构：[1]Department of Radiation Oncology, Sichuan Cancer Hospital, Chengdu, Sichuan, China[*1]Department of Radiation Oncology, Sichuan Cancer Hospital, 55 Renmin South Road, Chengdu 610041, Sichuan, China.
推荐引用方式(GB/T 7714)：
Liao Xiongfei,Lang Jinyi,Li Ningshan,et al.Dosimetric comparisons of IMRT planning using MCO and DMPO techniques[J].TECHNOLOGY AND HEALTH CARE.2017,25:S107-S114.doi:10.3233/THC-171312.
APA：
Liao, Xiongfei,Lang, Jinyi,Li, Ningshan,Wang, Pei,Li, Jie...&Chen, Yazheng.(2017).Dosimetric comparisons of IMRT planning using MCO and DMPO techniques.TECHNOLOGY AND HEALTH CARE,25,
MLA：
Liao, Xiongfei,et al."Dosimetric comparisons of IMRT planning using MCO and DMPO techniques".TECHNOLOGY AND HEALTH CARE 25.(2017):S107-S114
