机构：[1]Department of Cancer Prevention and Treatment, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China,四川省人民医院四川省肿瘤医院[2]Intensive Care Unit, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China,四川省人民医院[3]Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China,四川省人民医院四川省肿瘤医院[4]School of Public Health, Sun Yat-sen University, Guangzhou, China
Cystic echinococcosis (CE), a devastating zoonotic condition caused by the tapeworm Echinococcus granulosus, remain a significant public health problem worldwide. However, after a negative correlation between solid tumor and CE has been incidentally discovered, accumulating evidence have suggested that this parasite may induce anticancer effect through activating host immune response and secreting molecules with anticancer potential, which may provide some new understanding for immunotherapy. This article will review the evidence supporting the anticancer effect of E. granulosus and its underlying mechanisms and discuss the possible implications in immunotherapy.
基金：
The publication of this review has been funded by A Major Infectious Disease Prevention and Control of the National Science and Technique Major Project (NO. 2018ZX10715004), Project from Department of Education of Sichuan (NO. 18ZB0241) and Research Project from Sichuan Health and Family Planning Commission (NO.16PJ511 ).
第一作者机构：[1]Department of Cancer Prevention and Treatment, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China,
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Wang Guan,Xiaoqin Zhang,Xiao Wang,et al.Employing Parasite Against Cancer: A Lesson From the Canine Tapeworm Echinococcus Granulocus[J].FRONTIERS IN PHARMACOLOGY.2019,10:doi:10.3389/fphar.2019.01137.
APA：
Wang Guan,Xiaoqin Zhang,Xiao Wang,Shun Lu,Jun Yin&Jinxin Zhang.(2019).Employing Parasite Against Cancer: A Lesson From the Canine Tapeworm Echinococcus Granulocus.FRONTIERS IN PHARMACOLOGY,10,
MLA：
Wang Guan,et al."Employing Parasite Against Cancer: A Lesson From the Canine Tapeworm Echinococcus Granulocus".FRONTIERS IN PHARMACOLOGY 10.(2019)
