机构：[1]Department of Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University[2]Department of Medical Oncology, Sun Yat-sen University Cancer Center临床科室内科中山大学肿瘤防治中心[3]Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun YatSen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China
To determine whether inflammatory markers, derived neutrophil-to-lymphocyte ratio (dNLR), haemoglobin/platelet ratio (HPR) or platelet/lymphocyte ratio (PLR) are predictive for prognosis in angioimmunoblastic T-cell lymphoma (AITL), we derived dNLR, HPR and PLR values for 110 AITL patients and appropriate cut-off point values to define overall survival (OS) and progression-free survival (PFS). dNLR >= 2 center dot 2, HPR >= 0 center dot 4 or PLR < 100 were significant factors for shorter OS and PFS. On univariate analysis, these three parameters were significantly associated with worse OS and PFS. On multivariate analysis, only dNLR remained a significant, independent prognostic factor for both OS and PFS.
基金：
National Science and Technology Major Project [2020ZX09201021]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81572596, 81972471, U1601223]; Natural Science Foundation of Guangdong ProvinceNational Natural Science Foundation of Guangdong Province [2017A030313828]; Guangdong Science and Technology Department [2017B020227002, 2017B030314026]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2020]版：
大类|2 区医学
小类|2 区血液学
最新[2023]版：
大类|2 区医学
小类|2 区血液学
第一作者：
第一作者机构：[1]Department of Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University
通讯作者：
通讯机构：[*1]Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Department of Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiang West Road, Guangzhou, 510120, China
推荐引用方式(GB/T 7714)：
Huangming Hong,Xiaojie Fang,He Huang,et al.The derived neutrophil-to-lymphocyte ratio is an independent prognostic factor in patients with angioimmunoblastic T-cell lymphoma[J].BRITISH JOURNAL OF HAEMATOLOGY.2020,-.doi:10.1111/bjh.16447.
APA：
Huangming Hong,Xiaojie Fang,He Huang,Zhao Wang,Tongyu Lin&Herui Yao.(2020).The derived neutrophil-to-lymphocyte ratio is an independent prognostic factor in patients with angioimmunoblastic T-cell lymphoma.BRITISH JOURNAL OF HAEMATOLOGY,,
MLA：
Huangming Hong,et al."The derived neutrophil-to-lymphocyte ratio is an independent prognostic factor in patients with angioimmunoblastic T-cell lymphoma".BRITISH JOURNAL OF HAEMATOLOGY .(2020):-
医学