Purpose Patients with locally advanced rectal cancer treated with neoadjuvant CRT and who achieved pCR from January 2004 to December 2012 were collected. The primary outcome measurement was the patterns of recurrence. Results Among 195 patients who achieved pCR, 18 developed recurrence. Furthermore, local recurrence occurred in 1.5% of patients (3/195), while distant metastases occurred in 7.7% of patients (15/195), which included 7 lung metastases, 1 liver metastasis, and 8 metastases in other locations. Conclusions Our study indicated that patients achieving pCR following neoadjuvant CRT have a favorable prognosis, with distant metastases predominating in all recurrences. Among patients with distant metastases, non-liver metastases were the predominant pattern.
基金：
Nature Science Foundation of ChinaNational Natural Science Foundation of China [81101591]; Natural Science Foundation of Guangdong Province, ChinaNational Natural Science Foundation of Guangdong Province [S2011040005278, 9151008901000157]; Science and Technology Planning Project of Guangdong Province, China [2010B060900043]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2017]版：
大类|3 区医学
小类|3 区肿瘤学
最新[2023]版：
大类|3 区医学
小类|4 区肿瘤学
第一作者：
第一作者机构：[1]Collaborat Innovat Ctr Canc Med, State Key Lab Oncol South China, 651 Dongfeng Rd East, Guangzhou 510060, Guangdong, Peoples R China;[2]Sun Yat Sen Univ, Canc Ctr, Dept Colorectal Surg, Guangzhou, Guangdong, Peoples R China;
通讯作者：
通讯机构：[1]Collaborat Innovat Ctr Canc Med, State Key Lab Oncol South China, 651 Dongfeng Rd East, Guangzhou 510060, Guangdong, Peoples R China;[2]Sun Yat Sen Univ, Canc Ctr, Dept Colorectal Surg, Guangzhou, Guangdong, Peoples R China;[6]Sun Yat Sen Univ, Affiliated Hosp 6, Dept Colorectal Surg, Guangzhou, Guangdong, Peoples R China
推荐引用方式(GB/T 7714)：
Fan Wen-Hua,Xiao Jian,An Xin,et al.Patterns of recurrence in patients achieving pathologic complete response after neoadjuvant chemoradiotherapy for rectal cancer[J].JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY.2017,143(8):1461-1467.doi:10.1007/s00432-017-2383-9.
APA：
Fan, Wen-Hua,Xiao, Jian,An, Xin,Jiang, Wu,Li, Li-Ren...&Ding, Pei-Rong.(2017).Patterns of recurrence in patients achieving pathologic complete response after neoadjuvant chemoradiotherapy for rectal cancer.JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY,143,(8)
MLA：
Fan, Wen-Hua,et al."Patterns of recurrence in patients achieving pathologic complete response after neoadjuvant chemoradiotherapy for rectal cancer".JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 143..8(2017):1461-1467
