Objective: This study provides a comprehensive overview of Urology Oncology Nursing, exploring its scope, roles, significance, and challenges, while highlighting opportunities for professional growth and future trends in the field. Through literature review and expert insights, it examines the evolving role of Urology Oncology Nurses in cancer care and innovative approaches to patient needs. Subjects and Methods: A systematic analysis of scholarly literature, including studies, guidelines, and expert opinions, was conducted. Key focus areas included patient care models, assessment and diagnosis, monitoring and management strategies, patient education, support systems, and interdisciplinary collaboration. Results: Urology Oncology Nursing is pivotal in holistic urologic cancer care, emphasizing patient-centered approaches amid challenges and opportunities. The study identifies emerging trends, interdisciplinary collaboration, and the growing recognition of nurses' roles in optimizing outcomes. It underscores the need for adaptive strategies to address evolving healthcare demands. Conclusions: Urology Oncology Nursing is essential for improving patient outcomes, requiring sustained investment, professional development, and interdisciplinary partnerships. Integrating evidence-based practices and innovative technologies is critical to advancing care quality and meeting patient needs. The study advocates for continued focus on this specialty to drive transformative change in cancer care.