机构：[1]University of Electronic Science and Technology of China, School of Medicine, Chengdu, China. [2]Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Basic Research Center, Chengdu, China. 四川省肿瘤医院[3]Chengdu University of Traditional Chinese Medicine, School of Basic Medical Sciences, Chengdu, China. [4]Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Department of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan Province,, Chengdu, China. 四川省肿瘤医院[5]Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, Affiliated Cancer Hospital of University of Electronic Science and Technology of China, Department of Radiation Oncology, Radiation Oncology Key Laboratory of Sichuan Province, Chengdu, China四川省肿瘤医院
Intestinal resident CX3CR1+ macrophages are derived from embryos and replenished from peripheral circulating
monocytes through a "monocyte waterfall" process depending on CCL2/CCR2 axis. The turnover kinetics and
function of intestinal resident macrophage subpopulations during radiation and the underlying mechanisms
remains poorly defined. Herein, we used genetic modified mouse Ccr2RFP/+ Cx3cr1GFP/+ (R2X3), Ccr2RFP/RFPCx3cr1+/+
(R2-KO) and Ccr2+/+Cx3cr1GFP/GFP (X3-KO) mice were used for cell tracking and to dissect chemokine receptor CCR2
and CX3CR1 function in murine radiation enteritis model.
语种：
外文
WOS：
中科院(CAS)分区：
出版当年[2024]版：
无
最新[2023]版：
大类|1 区医学
小类|2 区肿瘤学2 区核医学
JCR分区：
出版当年[2024]版：
无
最新[2023]版：
Q1ONCOLOGYQ1RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
第一作者机构：[1]University of Electronic Science and Technology of China, School of Medicine, Chengdu, China.
推荐引用方式(GB/T 7714)：
Wang Zihao,Xiao Jie,Yao Jie,et al.Radiation induced intestinal resident macrophage turnover is regulated by microbiota[J].RADIOTHERAPY AND ONCOLOGY.2024,194:S5305-S5307.
APA：
Wang, Zihao,Xiao, Jie,Yao, Jie,Cao, Minmin,Xiang, Binghua...&Zhao, Yue.(2024).Radiation induced intestinal resident macrophage turnover is regulated by microbiota.RADIOTHERAPY AND ONCOLOGY,194,
MLA：
Wang, Zihao,et al."Radiation induced intestinal resident macrophage turnover is regulated by microbiota".RADIOTHERAPY AND ONCOLOGY 194.(2024):S5305-S5307
医学