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Creating a Standardized Tool for the Evaluation and Comparison of Artificial Intelligence-Based Computer-Aided Detection Programs in Colonoscopy: a Modified Delphi Approach

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机构: [1]Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA [2]Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan [3]Clinical Effectiveness Research Group, Institute of Health and Society, University of Oslo, Oslo, Norway [4]Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway [5]Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford, UK [6]Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, UK [7]Department of Gastroenterology, Humanitas Clinical and Research Center, IRCCS, Milan, Italy [8]Humanitas University, Department of Biomedical Sciences, Pieve Emanuele, Milan, Italy [9]Division of Gastroenterology, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada [10]Satisfai Health, Vancouver, British Columbia, Canada [11]Division of Gastroenterology, Montréal University Hospital and Research Center, Montreal, Canada [12]School of Medicine, The University of Queensland, Brisbane, Australia [13]Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, China [14]Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan [15]Gastrointestinal Endoscopy Unit, Gastroenterology Department, University of São Paulo Medical School, São Paulo, Brazil [16]Wellcome/EPSRC Centre for Interventional & Surgical Sciences, University College London, London, UK [17]Division of Gastroenterology and Hepatology, University of Kansas School of Medicine and VA Medical Center, Kansas City, USA [18]Division of Gastroenterology and Hepatology, New York University Langone Health System, New York, New York, USA [19]Section of Gastroenterology, University of Chicago Medicine, Chicago, Illinois, USA [20]Section of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA [21]Cosmo Intelligent Medical Devices, Dublin, Ireland [22]Wision AI, Palo Alto, California, USA [23]Odin Vision, London, UK [24]Olympus Corporation, Tokyo, Japan [25]Pentax Medical Europe, Hamburg, Germany [26]Magentiq Eye, Haifa, Israel [27]FUJIFILM Healthcare Americas Corporation, Lexington, Massachusetts, USA [28]Center for Advanced Endoscopy, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA [29]Division of Gastroenterology, Duke University Medical Center, Durham, North Carolina, USA
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关键词: Colonoscopy artificial intelligence computer-aided detection sensitivity adenoma detection rate

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Multiple computer-aided detection (CADe) software have now achieved regulatory approval in the US, Europe, and Asia and are being used in routine clinical practice to support colorectal cancer screening. There is uncertainty regarding how different CADe algorithms may perform. No objective methodology exists for comparing different algorithms. We aimed to identify priority scoring metrics for CADe evaluation and comparison.A modified Delphi approach was used. Twenty-five global leaders in CADe in colonoscopy, including endoscopists, researchers, and industry representatives, participated in an online survey over the course of 8 months. Participants generated 121 scoring criteria, 54 of which were deemed within the study scope and distributed for review and asynchronous email-based open comment. Participants then scored criteria in order of priority on a 5-point Likert scale during ranking round one. The top eleven highest-priority criteria were re-distributed, with another opportunity for open-comment, followed by a final round of priority scoring to identify the final 6 criteria.Mean priority scores for the 54 criteria ranged from 2.25 to 4.38 following the first ranking round. The top eleven criteria following ranking round one yielded mean priority scores ranging from 3.04 to 4.16. The final six highest priority criteria were 1) sensitivity (average = 4.16) and separate & independent validation of the CADe algorithm (4.16), 3) adenoma detection rate (4.08), 4) false positive rate (4.00), 5) latency (3.84), and 6) adenoma miss rate (3.68).This is the first reported international consensus statement of priority scoring metrics for CADe in colonoscopy. These scoring criteria should inform CADe software development and refinement. Future research should validate these metrics on a benchmark video data set to develop a validated scoring instrument.Copyright © 2024 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

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大类 | 1 区 医学
小类 | 2 区 胃肠肝病学
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大类 | 1 区 医学
小类 | 2 区 胃肠肝病学
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Q1 GASTROENTEROLOGY & HEPATOLOGY
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Q1 GASTROENTEROLOGY & HEPATOLOGY

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第一作者机构: [1]Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA
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