机构:[1]Department of Gynecological Cancer, Institute of Women and Children's Health, West China Second University Hospital, Sichuan University, Chengdu, China
Clinical and potential applications of ultrasonic therapy for gynecologic tumors are overviewed in this minireview. As a noninvasive technique, extracorporeal high-intensity focused ultrasound was clinically used to treat uterine myomas. High-intensity focused ultrasound treats leiomyomas via shrinkage of tumor size, reduction of blood supply, and suppression of cell proliferation, resulting in a relief of symptoms and improvement of quality of life. Preclinical trials have confirmed that ultrasound enhanced a cytotoxic agent against cancers of ovary and cervix; insonation overcomes doxorubicin (adriamycin) and cisplatin resistance in ovarian cancers, suggesting a modality for refractory lesions; ultrasonic hyperthermia induces high temperature increase in deeper cancer tissues thus being a potential modality for treatment of cervical cancers. Transvaginal ultrasonic therapy can be applied for a lesion near the cervix. In summary, ultrasonic therapy is a promising treatment modality for gynecologic tumors, and might change clinical practices.
基金:
Natural Science Foundation of China
(30670550, 10774198) and State Ministry of Education (NCET-05-0775,
SRFDP 20060631001).
语种:
外文
PubmedID:
中科院(CAS)分区:
出版当年[2008]版:
大类|4 区医学
小类|4 区妇产科学
最新[2023]版:
大类|2 区医学
小类|2 区妇产科学
第一作者:
第一作者机构:[1]Department of Gynecological Cancer, Institute of Women and Children's Health, West China Second University Hospital, Sichuan University, Chengdu, China[*1]Department of Gynecological Cancer, Institute of Women and Children’s Health, West China Second University Hospital, Sichuan University, Chengdu 610041, China
共同第一作者:
通讯作者:
通讯机构:[1]Department of Gynecological Cancer, Institute of Women and Children's Health, West China Second University Hospital, Sichuan University, Chengdu, China[*1]Department of Gynecological Cancer, Institute of Women and Children’s Health, West China Second University Hospital, Sichuan University, Chengdu 610041, China
推荐引用方式(GB/T 7714):
Yu Tinghe,Zhou Su,Zhang Jiao.Ultrasonic therapy for gynecologic tumors.[J].Journal of minimally invasive gynecology.2008,15(6):667-72.doi:10.1016/j.jmig.2008.07.018.
APA:
Yu Tinghe,Zhou Su&Zhang Jiao.(2008).Ultrasonic therapy for gynecologic tumors..Journal of minimally invasive gynecology,15,(6)
MLA:
Yu Tinghe,et al."Ultrasonic therapy for gynecologic tumors.".Journal of minimally invasive gynecology 15..6(2008):667-72