Accuracy of Pulmonary Nodule Volumetry Using Noise-Optimized Virtual Monoenergetic Image and Nonlinear Blending Image Algorithms in Dual-Energy Computed Tomography: A Phantom Study.
机构：[1]Department of Radiology, Sichuan Cancer Hospital &Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China.四川省人民医院四川省肿瘤医院CT室放射影像诊治部肿瘤放射影像诊治中心下影像科影像科[2]Department of Cancer Prevention and Treatment, Sichuan Cancer Hospital &Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.四川省人民医院四川省肿瘤医院
The aim of the study was to assess accuracy of pulmonary nodule volumetry using noise-optimized virtual monoenergetic image (VMI+) and nonlinear blending image (NBI) algorithms in dual-energy computed tomography (DECT).An anthropomorphic chest phantom with 10 simulated nodules (5 solid nodules and 5 ground-glass opacities) was scanned using DECT80/Sn140kV, DECT100/Sn140kV, and single-energy CT (SECT120kV/200mAs), respectively. The dual-energy images were reconstructed using VMI+ (70 keV) and NBI algorithms. The contrast-to-noise ratio and absolute percentage error (APE) of nodule volume were measured to assess image quality and accuracy of nodule volumetry. The radiation dose was also estimated.
The contrast-to-noise ratio of SECT120kV/200mAs was significantly higher than that of NBI80/Sn140kV and VMI+80/Sn140kV (both corrected P < 0.05), whereas there were no significant differences between NBI100/sn140kV and SECT120kV/200mAs and between VMI+100/sn140kV and SECT120kV/200mAs (both corrected P > 0.05). The APE of SECT120kV/200mAs was significantly lower than that of NBI80/Sn140kV and VMI+80/Sn140kV in both types of nodules (all corrected P < 0.05), whereas there were no significant differences between VMI+100/sn140kV and SECT120kV/200mAs in solid nodules and between NBI100/Sn140kV and SECT120kV/200mAs in ground-glass opacities (both corrected P > 0.05). The radiation dose of DECT100/Sn140kV and DECT80/Sn140kV were significantly lower than that of SECT120kV/200mAs (both corrected P < 0.05).
The DECT100/sn140kV can ensure image quality and nodule volumetry accuracy with lower radiation dose compared with SECT120kV/200mAs. Specifically, the VMI+ algorithm could be used in solid nodules and NBI algorithm in ground-glass opacities.
基金：
This study was supported by Chengdu Science and Technology Program (Grant Number: 2018-YF05-01134-SN, 2018-YF05-01368-SN,2020-YF05-00123-SN).
第一作者机构：[1]Department of Radiology, Sichuan Cancer Hospital &Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China.
共同第一作者：
通讯作者：
通讯机构：[1]Department of Radiology, Sichuan Cancer Hospital &Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China.[*1]Department of Radiology, Sichuan Cancer Hospital & Institute, School of Medicine, University of Electronic Science and Technology of China, No. 55, Section 4, S Renmin Rd, Chengdu, Sichuan 610041, China
推荐引用方式(GB/T 7714)：
Changjiu He,Jieke Liu,Shibei Hu,et al.Accuracy of Pulmonary Nodule Volumetry Using Noise-Optimized Virtual Monoenergetic Image and Nonlinear Blending Image Algorithms in Dual-Energy Computed Tomography: A Phantom Study.[J].JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY.2020,44(6):847-851.doi:10.1097/RCT.0000000000001102.
APA：
Changjiu He,Jieke Liu,Shibei Hu,Haomiao Qing,Liang Qiao...&Peng Zhou.(2020).Accuracy of Pulmonary Nodule Volumetry Using Noise-Optimized Virtual Monoenergetic Image and Nonlinear Blending Image Algorithms in Dual-Energy Computed Tomography: A Phantom Study..JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY,44,(6)
MLA：
Changjiu He,et al."Accuracy of Pulmonary Nodule Volumetry Using Noise-Optimized Virtual Monoenergetic Image and Nonlinear Blending Image Algorithms in Dual-Energy Computed Tomography: A Phantom Study.".JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY 44..6(2020):847-851
