高级检索
当前位置: 首页 > 详情页

Clinicopathological characteristics and outcome of patients with small cell neuroendocrine carcinoma of the uterine cervix: Case series and literature review

| 导出 |

文献详情

资源类型:
机构: [a]Department of Medical Oncology, Sichuan Cancer Hospital, Chengdu, Sichuan, China [b]Department of Information, Sichuan Cancer Hospital, Chengdu, Sichuan, China [c]Department of Pathology, Sichuan Cancer Hospital, Chengdu, Sichuan, China [d]Department of Gynecology Oncology, Sichuan Cancer Hospital, 55, 4th Section, Renmin Road, South Chengdu 610041, Sichuan, China
出处:
ISSN:

关键词: Clinical characteristics Immunohistochemistry Small cell neuroendocrine carcinoma Survival Uterine cervix

摘要:
Objective: To analyze the clinicopathological data of 13 cases of small cell neuroendocrine carcinoma (SCNEC) of the uterine cervix who received treatment at this medical institutions over the past five years with patient survival as the primary endpoint. Materials and Methods: The clinicopathologic data of 13 cases were reviewed. Immunohistochemistry was performed using antibodies against synaptophysin and chromogranin A and Ki-67. Survival was analyzed using the Kaplan-Meier method and log-rank tests. Results: The median age of these patients was 37 years (range 21-62). Immunohistochemistry showed that the positive rate of synaptophysin and chromogranin A was 100% (13/13) and 69.23% (9/13), respectively. The median survival of patients with early-Stage I-II SCNEC of the uterine cervix (17.5 months) was significantly higher than that of patients with advanced stage SCNEC of the uterine cervix (four months) (p < 0.05). There was no local recurrence in all 13 patients. Five patients died of distant metastasis in less than six months. Conclusion: SCNEC of the uterine cervix is a highly-malignant disease and early-stage patients showed significantly longer survival compared to late-stage patients. Early diagnosis and prompt combination treatment may improve the outcome of patients with SCNEC of the uterine cervix.

语种:
中科院(CAS)分区:
出版当年[2013]版:
大类 | 4 区 医学
小类 | 4 区 妇产科学 4 区 肿瘤学
最新[2023]版:
大类 | 4 区 医学
小类 | 4 区 妇产科学 4 区 肿瘤学
第一作者:
第一作者机构: [a]Department of Medical Oncology, Sichuan Cancer Hospital, Chengdu, Sichuan, China
通讯作者:
推荐引用方式(GB/T 7714):
APA:
MLA:

资源点击量:53699 今日访问量:0 总访问量:4607 更新日期:2025-02-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 四川省肿瘤医院 技术支持:重庆聚合科技有限公司 地址:成都市人民南路四段55号