机构：[1]Department of Obstetrics and Gynecology, The First Affiliated Hospital of Xiamen University, Xiamen, People’s Republic of China[2]Department of Radiation Oncology, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, People’s Republic of China[3]Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, People’s Republic of China临床科室其他部门放疗科华南肿瘤学国家重点实验室中山大学肿瘤防治中心[4]Eye Institute of Xiamen University, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Medical College of Xiamen University, Xiamen, People’s Republic of China[5]Faculty of Basic Medicine, Medical College, Xiamen University, Xiamen, People’s Republic of China
To investigate the clinicopathological characteristics and survival of small cell carcinoma of the cervix using Surveillance, Epidemiology, and End Results database. Patients with a diagnosis of small cell carcinoma of the cervix were included between 1988 and 2012. Kaplan-Meier method and Cox regression models were used. A total of 487 patients were included. Of the patients with known International Federation of Gynecology and Obstetrics stage and tumor grade, the stage IV disease was diagnosed in 37.9% patients, and 98.5% patients had poorly or undifferentiated histology. The 5-year cause specific survival and overall survival were 33.0% and 29.4%, respectively. In multivariate analysis, increasing age, advanced stage, and treatment by primary radiotherapy were associated with worse survival outcomes. Small cell carcinoma of the cervix is a rare disease with aggressive characteristics and prone to metastasize and is dismal in prognosis. Reduced survival was associated with increasing age, advanced stage, and treatment by primary radiotherapy.
基金：
Natural Science Foundation of Fujian Province [2015J01550]; Foundation Medical innovation Foundation of Fujian Province [2015-CXB-34]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2017]版：
大类|2 区医学
小类|2 区肿瘤学3 区细胞生物学
最新[2023]版：
无
第一作者：
第一作者机构：[1]Department of Obstetrics and Gynecology, The First Affiliated Hospital of Xiamen University, Xiamen, People’s Republic of China
共同第一作者：
通讯作者：
通讯机构：[3]Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, People’s Republic of China[5]Faculty of Basic Medicine, Medical College, Xiamen University, Xiamen, People’s Republic of China
推荐引用方式(GB/T 7714)：
Zhou Juan,Wu San-Gang,Sun Jia-Yuan,et al.Clinicopathological features of small cell carcinoma of the uterine cervix in the surveillance, epidemiology, and end results database[J].ONCOTARGET.2017,8(25):40425-40433.doi:10.18632/oncotarget.16390.
APA：
Zhou, Juan,Wu, San-Gang,Sun, Jia-Yuan,Tang, Li-Ying,Lin, Huan-Xin...&He, Zhen-Yu.(2017).Clinicopathological features of small cell carcinoma of the uterine cervix in the surveillance, epidemiology, and end results database.ONCOTARGET,8,(25)
MLA：
Zhou, Juan,et al."Clinicopathological features of small cell carcinoma of the uterine cervix in the surveillance, epidemiology, and end results database".ONCOTARGET 8..25(2017):40425-40433
