资源类型：
期刊
文章类型：
论著
机构：
[1]Department of Head and Neck Surgery, Sichuan Cancer Hospital, Chengdu, China
外科中心
头颈外科中心
四川省肿瘤医院
头颈外科
[2]Department of Otolaryngology-Head and Neck Surgery, the Affiliated Yuhuangding Hospital of Qingdao University, Yantai, China
[3]Department of Head and Neck Surgery , University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
[4]Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
ISSN：
0001-6519
关键词：
Cervical lymph node
Differentiated thyroid carcinoma
Metastasis
Neck lymph node dissection
摘要：
Background: Cervical lymph node metastasis (LNM) has been proven to be a predictor for locoregional recurrence in differentiated thyroid carcinoma (DTC). Clinicopathological features could be effective predictive factors for central and lateral LNM of DTC, and provide references to surgeons for cervical neck dissection. Methods: Retrospective analysis of clinicopathological data was performed on 420 patients who underwent initial surgery from 2010 to 2015. Results: The incidence of central and lateral LNM was calculated. Of 420 patients, 247 (58.8%) exhibited central LNM, and 185 (44.1%) exhibited lateral LNM. There were 29 (6.9%) cases confirmed to have skip metastasis. Univariate and multivariate analysis revealed that tumour location, tumour size, multifocality, capsular invasion, affected lobes, and age were independent predictors of central LNM. Tumour location, capsular invasion, affected lobes, and tumour size were independent predictors of lateral LNM. Conclusions: Our findings suggest that tumour location, affected lobes, capsular invasion, age, tumour size and multifocality may be taken as predictive factors for cervical LNM of DTC. Meticulous perioperative evaluation of cervical LNM and prophylactic cervical lymph node dissection that aims to remove the occult lymph nodes may be an option for DTC with risk factors. © 2017
第一作者：
Ronghao Sun
第一作者机构：
[1]Department of Head and Neck Surgery, Sichuan Cancer Hospital, Chengdu, China
共同第一作者：
Hua Zhang
通讯作者：
Xicheng Song;Chao Li
推荐引用方式(GB/T 7714)：
Ronghao Sun,Hua Zhang,Kun Liu,et al.Clinicopathologic Predictive Factors of Cervical Lymph Node Metastasis in Differentiated Thyroid Cancer[J].Acta Otorrinolaringologica Espanola.2018,69(3):doi:10.1016/j.otorri.2017.06.002.
APA：
Ronghao Sun,Hua Zhang,Kun Liu,Jinchuan Fan,Guojun Li...&Chao Li.(2018).Clinicopathologic Predictive Factors of Cervical Lymph Node Metastasis in Differentiated Thyroid Cancer.Acta Otorrinolaringologica Espanola,69,(3)
MLA：
Ronghao Sun,et al."Clinicopathologic Predictive Factors of Cervical Lymph Node Metastasis in Differentiated Thyroid Cancer".Acta Otorrinolaringologica Espanola 69..3(2018)
