机构：[1]Radiation Oncology Department, Sichuan Cancer Hospital, Chengdu, 610041, People’s Republic of China四川省肿瘤医院[2]Department of Radiation Oncology,Fox Chase Cancer Center, Philadelphia, PA, USA[3]Department of Radiation Oncology,Eye Ear Nose & Throat Hospital of Fudan University, Shanghai, People’s Republic of China
Pulsed low-dose-rate radiotherapy (PLDR) has been proven to be a valid method of reirradiation. Previous studies of recurrent cancer radiotherapy were mainly based on conventional 3D CRT and VMAT delivery techniques. There are difficulties in IMRT planning using existing commercial treatment planning systems (TPS) to meet the PLDR protocol. This work focuses on PLDR using ten-field IMRT and a commercial TPS for two specific sites: recurrent lung cancers and head and neck cancers. Our PLDR protocol requires that the maximum dose to the PTV be less than 0.4 Gy and the mean dose to be 0.2 Gy per field. We investigated various planning strategies to meet the PLDR requirements for 20 lung and head and neck patients. The PTV volume for lung cases ranged from 101.7 to 919.4 cm(3) and the maximum dose to the PTV ranged from 0.22 to 0.39 Gy. The PTV volume for head and neck cases ranged from 66.2 to 282.1 cm(3) and the maximum dose to the PTV ranged from 0.21 to 0.39 Gy. With special beam arrangements and dosimetry parameters, it is feasible to use a commercial TPS to generate quality PLDR IMRT plans for lung and head and neck reirradiation.
第一作者机构：[1]Radiation Oncology Department, Sichuan Cancer Hospital, Chengdu, 610041, People’s Republic of China
共同第一作者：
通讯作者：
通讯机构：[2]Department of Radiation Oncology,Fox Chase Cancer Center, Philadelphia, PA, USA[*1]Fox Chase Cancer Center, 333 Cottman Ave., Philadelphia, PA 19111, USA
推荐引用方式(GB/T 7714)：
Kang Shengwei,Lang Jinyi,Wang Pei,et al.Optimization strategies for pulsed low-dose-rate IMRT of recurrent lung and head and neck cancers[J].JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS.2014,15(3):102-113.doi:10.1120/jacmp.v15i3.4661.
APA：
Kang, Shengwei,Lang, Jinyi,Wang, Pei,Li, Jie,Lin, Muhan...&Ma, Chang Ming.(2014).Optimization strategies for pulsed low-dose-rate IMRT of recurrent lung and head and neck cancers.JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS,15,(3)
MLA：
Kang, Shengwei,et al."Optimization strategies for pulsed low-dose-rate IMRT of recurrent lung and head and neck cancers".JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS 15..3(2014):102-113
