机构:[1]Department of[2]Department of[3]Fogarty Global Health Fellowship,Vanderbilt University School of Medicine, Nashville,Tennessee, USA[4]dMedical Scholars Research Program, Vanderbilt University School of Medicine, Nashville,Tennessee, USA[5]Department of Breast Surgery, Liaoning Cancer Hospital, Shenyang, People’s Republic of China[6]Department of Breast-Thyroid Surgery, Second Xiangya Hospital, Central South University, Changsha, People’s Republic of China[7]Department of Breast Oncology, Sun Yat-Sen University Cancer Center, Gungzhou, People’s Republic of China[8]Department of Breast Surgery, Zhejiang Cancer Hospital, Hangzhou, People’s Republic of China浙江省肿瘤医院[9]Department of Oncosurgery, First Affiliated Hospital of Medical College, Xi’an Jiaotong University, Xi’an, People’s Republic of China[10]Department of Breast Surgery, Sichuan Cancer Hospital, Chengdu, People’s Republic of China外科中心乳腺外科中心四川省肿瘤医院乳腺科[11]Department of Epidemiology, West China School of Public Health, Sichuan University, Chengdu, Sichuan, People’s Republic of China
Background. Incidence rates of breast cancer continue to rise in the People's Republic of China. The purpose of this study was to describe Chinese trends in radical surgical modalities and influential imaging and demographic factors for breast malignancies. Materials and Methods. This study was a hospital-based, multicenter, 10-year (1999-2008), retrospective study. Descriptive statistical tests were used to illustrate information regarding radical surgical trends for the treatment of breast malignancies. Chi-square tests were used to assess effect of demographic factors in addition to imaging and pathological data on the specific surgical method. Results. A total of 4,211 patients were enrolled in the survey. Among them, 3,335 patients with stage 0 to stage III disease undergoing mastectomy or breast-conserving surgery (BCS) were included in the final analysis. The rate of BCS increased from 1.53% in 1999 to 11.88% in 2008. The rate of mastectomy declined over this time period, from 98.47% in 1999 to 88.12% in 2008, with increasing use of diagnostic imaging methods and pathological biopsies. A significantly greater percentage of patients with office work, high education levels, unmarried status, younger age, and early pathological stages preferred BCS compared with mastectomy. Conclusion. Rates of mastectomy in China remain elevated due to diagnosis at higher stages; however, because of increased use of diagnostic imaging, improvement of biopsy methods, and patient education, rates of less invasive lumpectomy are increasing and rates of mastectomy have decreased in China.
基金:
PfizerPfizer; NIH Fogarty International Center Grant [5R25TW009340]
通讯机构:[1]Department of[2]Department of[*1]Department of Breast Surgery, Cancer Institute/Hospital, Chinese Academy of Medical Sciences and Peking Union of Medical College, No. 17 Panjiayuannanli, Chaoyang District, Beijing 100021, People’s Republic of China[*2]Department of Epidemiology, Cancer Institute/Hospital, Chinese Academy of Medical Sciences and Peking Union of Medical College, No. 17 Panjiayuannanli, Chaoyang District, Beijing 100021, People’s Republic of China
推荐引用方式(GB/T 7714):
Zhang Bai-Lin,Sivasubramaniam Priya G.,Zhang Qian,et al.Trends in Radical Surgical Treatment Methods for Breast Malignancies in China: A Multicenter 10-Year Retrospective Study[J].ONCOLOGIST.2015,20(9):1036-1043.doi:10.1634/theoncologist.2014-0281.
APA:
Zhang, Bai-Lin,Sivasubramaniam, Priya G.,Zhang, Qian,Wang, Jing,Zhang, Bin...&Qiao, You-Lin.(2015).Trends in Radical Surgical Treatment Methods for Breast Malignancies in China: A Multicenter 10-Year Retrospective Study.ONCOLOGIST,20,(9)
MLA:
Zhang, Bai-Lin,et al."Trends in Radical Surgical Treatment Methods for Breast Malignancies in China: A Multicenter 10-Year Retrospective Study".ONCOLOGIST 20..9(2015):1036-1043