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Diffusion-Weighted Imaging of the Kidneys and Its Relationship With Residual Renal Function in Continuous Ambulatory Peritoneal Dialysis Patients

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收录情况： ◇ SCIE

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机构： [1]Department of Radiology, West China Hospital, Sichuan University, 37 Guoxue St, Chengdu 610041, Sichuan Province, China [2]Department of Radiology, Sichuan Cancer Hospital, Chengdu, Sichuan Province, China

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关键词： apparent diffusion coefficient continuous ambulatory peritoneal dialysis diffusion-weighted imaging residual renal function

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OBJECTIVE. The objective of our study was to prospectively evaluate renal diffusion as shown by diffusion-weighted imaging (DWI) and its relationship with the residual renal function (RRF) in continuous ambulatory peritoneal dialysis (CAPD) patients. SUBJECTS AND METHODS. Forty CAPD patients and 40 healthy volunteers were recruited, and all underwent conventional and fat-saturated echo-planar DWI with three b values (0, 300, 600 s/mm2). The renal parenchymal thickness and apparent diffusion coefficients (ADCs) were measured, and both were compared between the two groups. The relationships between ADC values and clinical indexes-which included RRF, serum creatinine value, cystatin C value, and urine output- were analyzed. RESULTS. Compared with the renal parenchymal thickness and ADC values in control subjects, these values in CAPD patients were significantly decreased (p < 0.0001). In CAPD patients, the ADC values were positively correlated with RRF (r = 0.447, p = 0.004). A mild linear correlation was also found between the ADC values and cystatin C value (r = -0.352,p = 0.026). CONCLUSION. The renal diffusion function as shown by DWI is impaired in CAPD patients and correlates with RRF.

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出版当年[2015]版：

大类 | 3 区医学

小类 | 3 区核医学

最新[2023]版：

大类 | 2 区医学

小类 | 2 区核医学

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出版当年[2015]版：

Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

最新[2023]版：

Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

影响因子： 4.7 最新[2023版] 4.1 最新五年平均 2.66 出版当年[2015版] 3.154 出版当年五年平均 2.731 出版前一年[2014版] 2.778 出版后一年[2016版]

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第一作者机构： [1]Department of Radiology, West China Hospital, Sichuan University, 37 Guoxue St, Chengdu 610041, Sichuan Province, China

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