机构:[1]Department of Hematology, Hematology Research Laboratory and Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China四川大学华西医院[2]Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA[3]Department of Internal Medicine and Pathology, The Sichuan Province Tumour Hospital, Chengdu, Sichuan, China[4]Department of Hematology and Pathology, The Sichuan Provincial People’s Hospital, Chengdu, Sichuan, China四川省人民医院[5]Department of Hematology, the affiliated Hospital of Luzhou Medical College.
Previous studies in other provinces of China (Beijing, Xinjiang, Shanxi, Jiangxi, Shanghai, Guangdong, and Taiwan) suggest that the distributions of lymphoma subtypes differ compared with Western populations. In order to evaluate the characteristics of malignant lymphoma in Sichuan, China, we analyzed case series data from incident lymphoma patients diagnosed in 2008 from three hospitals, including a total of 1629 cases and including only current residents of Sichuan. The median age of diagnosis for cases was 54years, with a higher proportion of male cases compared with female cases. The most commonly diagnosed subtypes included diffuse large B-cell lymphoma (40.4%), NK/T-cell lymphoma (NKTCL; 11.8%), mixed cellularity Hodgkin lymphoma (7.0%), mantle cell lymphoma (4.8%), and marginal zone B-cell lymphoma (3.9%). Differences in demographic characteristics between Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) cases were apparent for median age at diagnosis (HL: 34years; NHL: 57years), and NHLs accounted for nearly all (99.3%) of the 931 cases of extranodal lymphoma. These findings indicate a higher proportion of NKTCL cases and a lower proportion of follicular lymphoma cases (2.3%) in these hospitals in Sichuan, relative to reports from some other provinces within China (e.g., Shanghai and Shanxi) and the USA. Copyright (c) 2015 John Wiley & Sons, Ltd.
基金:
Intramural NIH HHSUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA [Z01 CP010123-12]
第一作者机构:[1]Department of Hematology, Hematology Research Laboratory and Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China[5]Department of Hematology, the affiliated Hospital of Luzhou Medical College.
共同第一作者:
通讯作者:
通讯机构:[1]Department of Hematology, Hematology Research Laboratory and Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China[*1]Department of Hematology, Hematology Research Laboratory and Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, China.
推荐引用方式(GB/T 7714):
Wang Xue-mei,Bassig Bryan A.,Wen Jing-jing,et al.Clinical analysis of 1629 newly diagnosed malignant lymphomas in current residents of Sichuan province, China[J].HEMATOLOGICAL ONCOLOGY.2016,34(4):193-199.doi:10.1002/hon.2202.
APA:
Wang, Xue-mei,Bassig, Bryan A.,Wen, Jing-jing,Li, Gan-di,Liu, Zhi-bin...&Xu, Cai-gang.(2016).Clinical analysis of 1629 newly diagnosed malignant lymphomas in current residents of Sichuan province, China.HEMATOLOGICAL ONCOLOGY,34,(4)
MLA:
Wang, Xue-mei,et al."Clinical analysis of 1629 newly diagnosed malignant lymphomas in current residents of Sichuan province, China".HEMATOLOGICAL ONCOLOGY 34..4(2016):193-199