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Dose tracking assessment for image-guided radiotherapy of the prostate bed and the impact on clinical workflow

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机构: [1]Centro Oncologico Fiorentino, Radiation Oncology Department, Via A. Ragionieri 101, 50023 Florence, Italy. [2]Department of Radiation Oncology, Sichuan Cancer Hospital, No.55, the 4th Section, Renmin South Road, Chengdu, China. [3]Azienda Ospedaliera di Perugia, Health Physics Department, Piazzale Menghini 1, 06129 Perugia, Italy.
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关键词: Radiotherapy Image-guided radiotherapy Intensi-modulated radiation therapy Prostate cancer

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Background: The cumulative dose was compared with the planned dose among fourteen patients undergoing image-guided, intensity-modulated radiotherapy of the prostate bed. Moreover, we investigated the feasibility of adding dose tracking to the routine workflow for radiotherapy. Methods: Daily cone beam computed tomography was conducted for image-guided radiotherapy, and weekly cumulative delivered doses were calculated for dose tracking. Deformable image registration was applied to map weekly dose distributions to the original treatment plan and to create a cumulative dose distribution. The dose-volume histogram (DVH) cut-off points for the rectum and bladder and the planning target volume (PTV), were used to compare the planned and cumulative delivered doses. The additional time required by the departmental staff to complete these duties was recorded. Results: The PTV coverage of the delivered treatment did not satisfy the expected goal for three patients (V98% > 98%). In another three patients, the DVH cut-off point for the bladder was higher than the limits, while for the rectum, treatment was as expected in all cases (two patients failed both their bladder constraints and the PTV coverage). Overall, four patients did not satisfy one or more criteria at the end of their treatment. Conclusions: A well-defined strategy for dose tracking assessment is feasible, would have minimal impact on the workload of a radiotherapy department, and may offer objective information to support radiation oncologists in making decisions about adaptive procedures.

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出版当年[2017]版:
大类 | 3 区 医学
小类 | 3 区 核医学 4 区 肿瘤学
最新[2023]版:
大类 | 2 区 医学
小类 | 2 区 核医学 3 区 肿瘤学
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出版当年[2017]版:
Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Q3 ONCOLOGY
最新[2023]版:
Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Q2 ONCOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2017版] 出版当年五年平均 出版前一年[2016版] 出版后一年[2018版]

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第一作者机构: [1]Centro Oncologico Fiorentino, Radiation Oncology Department, Via A. Ragionieri 101, 50023 Florence, Italy. [2]Department of Radiation Oncology, Sichuan Cancer Hospital, No.55, the 4th Section, Renmin South Road, Chengdu, China.
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