机构：[1]Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China四川省人民医院四川省肿瘤医院[2]Sichuan Center for Disease Control and Prevention, Chengdu, China[3]School of Electronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu, China
Due to the reported high incidence of thyroid cancer induced by radiotherapy, dose assessment is significant to prevent thyroid late effects. Thyroid dosimetry can be evaluated either by entrance skin dose (ESD) measured with thermoluminescent dosimeter (TLD) arrays or by absorbed dose (AD) computed with treatment planning system. However, their correlation has hardly been reported in any publications. Moreover, the reported measurement procedures for thyroid ESD are usually inefficient. This study aims to provide a fast model for efficient acquisition of thyroid ESD and analyze the coherent relationship between ESD and AD. We conducted the study on the China radiation anthropomorphic phantom with intentionally delineated cancers, irradiated by a Varian 23EX linac. We have measured the ESD with TLD at 5 different points, while computed AD with the Oncentra Masterplan TPS. The ESD at the middle gorge of thyroid has exhibited significant linear correlation with those measured at other points. Furthermore, a regressive model has been proposed to predict thyroid AD from ESD. Consequently, it is recommended to only measure the ESD at the middle gorge of thyroid for an efficient dose assessment. The validity of the regressive model to predict thyroid AD from ESD has also been demonstrated.
基金：
National Natural Science Foundation of China (NSFC)National Natural Science Foundation of China [61901087, 81903135, 81900498, 61701083]; Sichuan Science and Technology Program [2019YJ0581, 19ZDYF0853]
基金编号：NSFC
语种：
外文
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2019]版：
大类|4 区医学
小类|4 区药学4 区核医学
最新[2023]版：
大类|4 区医学
小类|4 区药学4 区核医学
JCR分区：
出版当年[2019]版：
Q2RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGINGQ3PHARMACOLOGY & PHARMACY
最新[2023]版：
Q2RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGINGQ3PHARMACOLOGY & PHARMACY
第一作者机构：[1]Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China
通讯作者：
通讯机构：[1]Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China[2]Sichuan Center for Disease Control and Prevention, Chengdu, China[*1]Sichuan Center for Disease Control and Prevention, Zhongxue Road No. 6, Chengdu 610041, China[*2]Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China
推荐引用方式(GB/T 7714)：
Wang Yiling,Zheng Min,He Ling,et al.Fast Model for Evaluation of the Thyroid Dosimetry During Chest Tumor Radiotherapy[J].DOSE-RESPONSE.2019,17(4):doi:10.1177/1559325819889152.
APA：
Wang, Yiling,Zheng, Min,He, Ling,Xu, Jinhui,Yin, Gang...&Wang, Jie.(2019).Fast Model for Evaluation of the Thyroid Dosimetry During Chest Tumor Radiotherapy.DOSE-RESPONSE,17,(4)
MLA：
Wang, Yiling,et al."Fast Model for Evaluation of the Thyroid Dosimetry During Chest Tumor Radiotherapy".DOSE-RESPONSE 17..4(2019)
