机构：[1]Department of Neurosurgery, Chinese PLA General Hospital and PLA Medical College, Beijing, China[2]Department of Functional Neurosurgery, Beijing Children’s Hospital, Capital Medical University, Beijing, China首都医科大学附属北京儿童医院[3]Department of Neuroelectrophysiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China首都医科大学附属天坛医院[4]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China首都医科大学附属天坛医院[5]Department of Neurosurgery, First Affiliated Hospital of PLA General Hospital, Beijing, China[6]Department of Molecular Neuropathology, Beijing Neurosurgery Institute, Capital Medical University, Beijing, China[7]Department of Neurosurgery, Second Affiliated Hospital, Hebei Medical University, Shijiazhuang, China[8]Department of Neurology, Shanghai Huashan Hospital, Fudan University, Shaihai, China[9]Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China[10]Department of Neurosurgery, Beijing Sanbo Hospital, Capital Medical University, Beijing, China[11]Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing,China[12]Department of Neurosurgery, Second Affiliated Hospital, Army Medical University, Chongqing, China[13]Department of Neurosurgery, First Affiliated Hospital of Nanjing Medical University, Nanjing, China江苏省人民医院[14]Department of Neurosurgery, Zhongda Hospital, Southeast University, Nanjing, China[15]Department of Neurosurgery, First Affiliated Hospital, Beijing University, Beijing, China[16]Department of Neurology, Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China[17]Department of Neurology, First Affiliated Hospital, Beijing University, Beijing, China[18]Department of Neurosurgery, Huaxi Hospital, Sichuan University, Chengdu, China四川大学华西医院[19]Department of Neurology, Beijing Xuanwu Hospital, Capital Medical University, Beijing, China首都医科大学宣武医院[20]Department of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China[21]Department of Neurology, First Affiliated Hospital, Chongqing Medical University, Chongqing, China重庆医科大学附属第一医院[22]Department of Neurosurgery, Second Affiliated Hospital of Harbin Medical University, Harbin, China[23]Pediatric Department, First Affiliated Hospital, Beijing University, Beijing, China[24]Department of Neurosurgery, Nanfang Hospital, Nanfang Medical University, Guangzhou, China[25]Epilepsy Center, Shanghai Deji Hospital, Shanghai, China[26]Department of Neurosurgery, Tangdu Hospital, Air Force Medical University, Xi’an, China[27]Department of Functional Neurosurgery, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China[28]Department of Neurosurgery, Guangzhou Military General Hospital, Guangzhou, China[29]Department of Neurology, Xiangya Third Hospital, Center South University, Changsha, China[30]Department of Neurosurgery, Shanghai Huashan Hospital, Fudan University, Shanghai, China[31]Department of Neurosurgery, Xiangya Hospital, Center South University, Changsha, China[32]Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China[33]Department of Neurology, Peking University International Hospital, Beijing, China[34]China Association Against Epilepsy (CAAE), Beijing, China
Background Glioma-related epilepsy (GRE) is defined as symptomatic epileptic seizures secondary to gliomas, it brings both heavy financial and psychosocial burdens to patients with diffuse glioma and significantly decreases their quality of life. To date, there have been no clinical guidelines that provide recommendations for the optimal diagnostic and therapeutic procedures for GRE patients. Methods In March 2017, the Joint Task Force for GRE of China Association Against Epilepsy and Society for Neuro-Oncology of China launched the guideline committee for the diagnosis and treatment of GRE. The guideline committee conducted a comprehensive review of relevant domestic and international literatures that were evaluated and graded based on the Oxford Centre for Evidence-Based Medicine Levels of Evidence, and then held three consensus meetings to discuss relevant recommendations. The recommendations were eventually given according to those relevant literatures, together with the experiences in the diagnosis and treatment of over 3000 GRE cases from 24 tertiary level hospitals that specialize in clinical research of epilepsy, glioma, and GRE in China. Results The manuscript presented the current standard recommendations for the diagnostic and therapeutic procedures of GRE. Conclusions The current work will provide a framework and assurance for the diagnosis and treatment strategy of GRE to reduce complications and costs caused by unnecessary treatment. Additionally, it can serve as a reference for all professionals involved in the management of patients with GRE.
第一作者机构：[1]Department of Neurosurgery, Chinese PLA General Hospital and PLA Medical College, Beijing, China[2]Department of Functional Neurosurgery, Beijing Children’s Hospital, Capital Medical University, Beijing, China
共同第一作者：
通讯作者：
通讯机构：[4]Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China[6]Department of Molecular Neuropathology, Beijing Neurosurgery Institute, Capital Medical University, Beijing, China[34]China Association Against Epilepsy (CAAE), Beijing, China[*1]Department of Neurosurgery, Beijing Tiantan Hospital/Department of Molecular Neuropathology, Beijing Neurosurgery Institute, Capital Medical University, Beijing, China.[*2]China Association Against Epilepsy (CAAE), Beijing, China
推荐引用方式(GB/T 7714)：
Shuli Liang,Xing Fan,Ming Zhao,et al.Clinical practice guidelines for the diagnosis and treatment of adult diffuse glioma-related epilepsy[J].CANCER MEDICINE.2019,8(10):4527-4535.doi:10.1002/cam4.2362.
APA：
Shuli Liang,Xing Fan,Ming Zhao,Xia Shan,Wenling Li...&Tao Jiang.(2019).Clinical practice guidelines for the diagnosis and treatment of adult diffuse glioma-related epilepsy.CANCER MEDICINE,8,(10)
MLA：
Shuli Liang,et al."Clinical practice guidelines for the diagnosis and treatment of adult diffuse glioma-related epilepsy".CANCER MEDICINE 8..10(2019):4527-4535
