Long-term Survival Based on the Surgical Approach to Lobectomy For Clinical Stage I Nonsmall Cell Lung Cancer Comparison of Robotic, Video-assisted Thoracic Surgery, and Thoracotomy Lobectomy
机构:[1]Mem Sloan Kettering Canc Ctr, Dept Surg, Thorac Serv, 1275 York Ave, New York, NY 10021 USA;[2]Sun Yat Sen Univ, Ctr Canc, Dept Thorac Surg, Collaborat Innovat Ctr Canc Med,State Key Lab Onc, Guangzhou, Guangdong, Peoples R China;临床科室胸科中山大学肿瘤防治中心[3]Mem Sloan Kettering Canc Ctr, Dept Epidemiol & Biostat, New York, NY 10021 USA;[4]Weill Cornell Med Coll, New York, NY USA;[5]Mem Sloan Kettering Canc Ctr, Thorac Serv, Clin Affairs, 1275 York Ave,Mailbox 533, New York, NY 10065 USA
Objective: To compare the long-term outcomes among robotic, video assisted thoracic surgery (VATS), and open lobectomy in stage I nonsmall cell lung cancer (NSCLC). Background: Survival comparisons between robotic. VATS, and open lobectomy in NSCLC have not yet been reported. Some studies have suggested that survival after VATS is superior, for unclear reasons. Methods: Three cohorts (robotic, VATS, and open) of clinical stage I NSCLC patients were matched by propensity score and compared to assess overall survival (OS) and disease-free survival (DES). Univariate and multivariate analyses were performed to identify factors associated with the outcomes. Results: From January 2002 to December 2012, 470 unique patients (172 robotic, 141 VATS, and 157 open) were included in the analysis. The robotic approach harvested a higher number of median stations of lymph nodes (5 for robotic vs 3 for VATS vs 4 for open; P < 0.001). Patients undergoing minimally invasive approaches had shorter median length or hospital stay (4d for robotic vs 4d for VATS vs 5 d for open; P <0001). The 5-year OS for the robotic, VATS, and open matched groups were 77.6%, 73.5%, and 77.9%, respectively, without a statistically significant difference; corresponding 5-year DFS were 72.7%, 65.5%, and 69.0%, respectively, with a statistically significant difference between the robotic and VATS groups (P = 0.047). However, multivariate analysis found that surgical approach was not independently associated with shorter OS and DFS. Conclusions: Minimally invasive approaches to lobectomy for clinical stage I NSCLC result in similar long-term survival as thoracotomy. Use of VATS and robotics is associated with shorter length of stay, and the robotic approach resulted in greater lymph node assessment.
基金:
National Institutes of Health/National Cancer Institute Cancer Center Support Grant [P30 CA008748]
语种:
外文
被引次数:
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PubmedID:
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出版当年[2017]版:
大类|1 区医学
小类|1 区外科
最新[2023]版:
大类|1 区医学
小类|1 区外科
第一作者:
第一作者机构:[1]Mem Sloan Kettering Canc Ctr, Dept Surg, Thorac Serv, 1275 York Ave, New York, NY 10021 USA;[2]Sun Yat Sen Univ, Ctr Canc, Dept Thorac Surg, Collaborat Innovat Ctr Canc Med,State Key Lab Onc, Guangzhou, Guangdong, Peoples R China;
通讯作者:
通讯机构:[1]Mem Sloan Kettering Canc Ctr, Dept Surg, Thorac Serv, 1275 York Ave, New York, NY 10021 USA;[4]Weill Cornell Med Coll, New York, NY USA;[5]Mem Sloan Kettering Canc Ctr, Thorac Serv, Clin Affairs, 1275 York Ave,Mailbox 533, New York, NY 10065 USA
推荐引用方式(GB/T 7714):
Yang Hao-Xian,Woo Kaitlin M.,Sima Camelia S.,et al.Long-term Survival Based on the Surgical Approach to Lobectomy For Clinical Stage I Nonsmall Cell Lung Cancer Comparison of Robotic, Video-assisted Thoracic Surgery, and Thoracotomy Lobectomy[J].ANNALS OF SURGERY.2017,265(2):431-437.doi:10.1097/SLA.0000000000001708.
APA:
Yang, Hao-Xian,Woo, Kaitlin M.,Sima, Camelia S.,Bains, Manjit S.,Adusumilli, Prasad S....&Park, Bernard J..(2017).Long-term Survival Based on the Surgical Approach to Lobectomy For Clinical Stage I Nonsmall Cell Lung Cancer Comparison of Robotic, Video-assisted Thoracic Surgery, and Thoracotomy Lobectomy.ANNALS OF SURGERY,265,(2)
MLA:
Yang, Hao-Xian,et al."Long-term Survival Based on the Surgical Approach to Lobectomy For Clinical Stage I Nonsmall Cell Lung Cancer Comparison of Robotic, Video-assisted Thoracic Surgery, and Thoracotomy Lobectomy".ANNALS OF SURGERY 265..2(2017):431-437