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The 150 most important questions in cancer research and clinical oncology series: Questions 25-30

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收录情况: ◇ 统计源期刊 ◇ CSCD-C

机构: [1]Sun Yat Sen Univ, Editorial Off, Chinese Journal Canc, Canc Ctr, Guangzhou 510060, Guangdong, Peoples R China; [2]NCI, Bethesda, MD 20892 USA; [3]Sun Yat Sen Univ, Canc Ctr, Guangzhou, Guangdong, Peoples R China; [4]Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA; [5]GlaxoSmithKline, London, England; [6]Dr Bhubaneswar Borooah Canc Inst, Gauhati, India
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关键词: Immune responses Immunotherapy Metastasis Cancer initiation

摘要:
To accelerate our endeavors to overcome cancer, Chinese Journal of Cancer has launched a program of publishing 150 most important questions in cancer research and clinical oncology. In this article, 6 more questions are presented as followed. Question 25: Does imprinting of immune responses to infections early in life predict future risk of childhood and adult cancers? Question 26: How to induce homogeneous tumor antigen expression in a heterogeneous tumor mass to enhance the efficacy of cancer immunotherapy? Question 27: Could we enhance the therapeutic effects of immunotherapy by targeting multiple tumor antigens simultaneously or sequentially? Question 28: Can immunotargeting to cytokines halt cancer metastasis? Question 29: How can we dynamically and less-invasively monitor the activity of CD8(+) T killer cells at tumor sites and draining lymph nodes? Question 30: How can the immune system destroy the niches for cancer initiation?

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出版当年[2017]版:
大类 | 3 区 医学
小类 | 3 区 肿瘤学
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第一作者机构: [2]NCI, Bethesda, MD 20892 USA;
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通讯机构: [2]NCI, Bethesda, MD 20892 USA;
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