Purpose: To explore the short-term efficacy and safety of CT-guided microwave ablation (MWA) for treating liver tumors near the diaphragm. Results: The complete response (CR) rate for CT-guided MWA through the lung was 94.7% (124/131). The incomplete response (ICR) rate was 5.3% (7/131), of which 6 patients with ICRs achieved CRs after MWA. The CR rate for Group I was higher than Group H (99.0% vs. 80.0%, P=0.001).The mean follow-up time was 11.2 +/- 7.50 months. The total local recurrence (LR) rate was 15.3% (20/131). The complication rate was 26.5%, and no severe complications were recorded. All complications were controllable and treatable. The incidence of diaphragmatic thickening during the MWA was 18.8% (P>0.05); the incidence of exudative changes inside the lungs was 6.8% (P>0.05). Conclusions: CT-guided MWA can detect changes in liver tissue, in the diaphragm and nearby lung tissues during the ablation process. It's safe and effective to treat tumors close to the diaphragm by CT-guided MWA through the lung. Methods: CT-guided MWA was used on 131 tumors that were close to the diaphragm (distance between tumor and diaphragm 5 5 mm) in 117 patients with liver cancer. The tumors were divided into a < 3.0 cm group (Group I, n= 101) and a 3.0 cm group (Group II, n= 30) based on tumor diameters. The complications within 2 weeks following treatment were counted, and the safety and short-term efficacy of MWA were analyzed.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81371651]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2017]版：
大类|2 区医学
小类|2 区肿瘤学3 区细胞生物学
最新[2023]版：
无
第一作者：
第一作者机构：[1]Sun Yat Sen Univ, Dept Imaging & Intervent Radiol, Collaborat Innovat Ctr Canc Med, Canc Ctr,State Key Lab Oncol South China, Guangzhou, Guangdong, Peoples R China;
通讯作者：
通讯机构：[1]Sun Yat Sen Univ, Dept Imaging & Intervent Radiol, Collaborat Innovat Ctr Canc Med, Canc Ctr,State Key Lab Oncol South China, Guangzhou, Guangdong, Peoples R China;
推荐引用方式(GB/T 7714)：
Qi Han,Zhang Hao,Wan Chao,et al.CT-guided microwave ablation through the lungs for treating liver tumors near the diaphragm[J].ONCOTARGET.2017,8(45):79270-79278.doi:10.18632/oncotarget.17422.
APA：
Qi, Han,Zhang, Hao,Wan, Chao,Xie, Lin,Song, Ze&Fan, Weijun.(2017).CT-guided microwave ablation through the lungs for treating liver tumors near the diaphragm.ONCOTARGET,8,(45)
MLA：
Qi, Han,et al."CT-guided microwave ablation through the lungs for treating liver tumors near the diaphragm".ONCOTARGET 8..45(2017):79270-79278
