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China Expert consensus on the application of metagenomic next-generation sequencing for the etiological diagnosis of infections in hematological disorders (2024)

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Pubmed体系：

收录情况： ◇ 统计源期刊 ◇ ESCI ◇ 中华系列

作者：
Xu, Chunhui[1,2] * ; Lin, Ren[3] * ; Bai, Ye[4] ; Han, Yanqiu[5] ; Hu, Jianda[6] ; Hu, Jiong[7] ; Hu, Yu[8] ; Huang, Fen[3] ; Huang, Xiaojun[9] ; Ji, Chunyan[10] ; Li, Xin[11] ; Liang, Aibin[1] ; Lu, Peihua[12] ; Ma, Jun[13] ; Mei, Heng[8] ; Niu, Ting[14] ; Ouyang, Jian[15] ; Qian, Wenbin[16] ; Shi, Jimin[17] ; Song, Yongping[18] ; Sun, Aining[19] ; Tan, Yehui[20] ; Wang, Hui[21] ; Wang, Jianxiang[1] ; Wang, Yu[9] ; Wu, Depei[19] ; Xiao, Zhijian[1,2] ; Yang, Ting[22] ; Zhang, Cheng[23] ; Zhang, Xi[23] ; Zhang, Xiaohui[9] ; Zhao, Weili[7] ; Zheng, Zhuanzhen[24] ; Zhu, Zunmin[25] ; Feng, Sizhou[1,2,*1,*2] ; Liu, Qifa[3] ;
机构： [1]Natl Clin Res Ctr Blood Dis, Inst Hematol, State Key Lab Expt Hematol, Haihe Lab Cell Ecosyst, Tianjin 300020, Peoples R China [2]Blood Dis Hosp, Tianjin 300020, Peoples R China [3]Southern Med Univ, Nanfang Hosp, Clin Med Res Ctr Hematol Dis Guangdong Prov, Dept Hematol, Guangzhou 510515, Guangzhou, Peoples R China [4]Tianjin Union Precis Med Diagnost CO LTD, Tianjin 300020, Peoples R China [5]Inner Mongolia Med Univ, Affiliated Hosp, Hohhot 010050, Peoples R China [6]Fujian Med Univ, Affiliated Hosp 2, Dept Hematol, Quanzhou 362000, Peoples R China [7]Shanghai Jiao Tong Univ, Sch Med, Ruijin Hosp, Dept Hematol, Shanghai 200025, Peoples R China [8]Huazhong Univ Sci & Technol, Union Hosp, Inst Hematol, Tongji Med Coll, Wuhan 430030, Peoples R China [9]Peking Univ, Inst Hematol, Natl Clin Res Ctr Hematol Dis,Peoples Hosp, Beijing Key Lab Hematopoiet Stem Cell Transplantat, Beijing 100044, Peoples R China [10]Shandong Univ, Qilu Hosp, Dept Hematol, Jinan 250012, Peoples R China [11]Cent South Univ, Xiangya Hosp 3, Dept Hematol, Changsha 412000, Peoples R China [12]Hebei Yanda Lu Daopei Hosp, Langfang 065201, Peoples R China [13]First Hosp Harbin, Inst Hematol & Oncol, Harbin 150010, Peoples R China [14]Sichuan Univ, West China Hosp, Inst Hematol, Dept Hematol, Chengdu 610041, Peoples R China [15]Nanjing Univ, Nanjing Drum Tower Hosp, Affiliated Hosp, Dept Hematol,Med Sch, Nanjing 210008, Peoples R China [16]Zhejiang Univ, Affiliated Hosp 2, Coll Med, Dept Hematol, Hangzhou 310009, Peoples R China [17]Zhejiang Univ, Affiliated Hosp 1, Ctr Hematol & Bone Marrow Transplantat, Sch Med, Hangzhou 310003, Peoples R China [18]Zhengzhou Univ, Henan Canc Hosp, Affiliated Canc Hosp, Dept Hematol, Zhengzhou 450008, Peoples R China [19]Soochow Univ, Affiliated Hosp 1, Jiangsu Inst Hematol, Suzhou 215006, Peoples R China [20]First Hosp Jilin Univ, Dept Stomatol, Changchun 130031, Peoples R China [21]Peking Univ, Dept Clin Lab, Peoples Hosp, Beijing 100044, Peoples R China [22]Fujian Med Univ, Affiliated Hosp 1, Natl Reg Med Ctr, Dept Hematol 2, Binhai Campus, Fuzhou 350209, Peoples R China [23]Army Med Univ, Xinqiao Hosp, Med Ctr Hematol, Chongqing 400037, Peoples R China [24]Shanxi Med Univ, Hosp 2, Taiyuan 030001, Peoples R China [25]Henan Prov Peoples Hosp, Dept Hematol, Zhengzhou 450003, Peoples R China
出处：
DOI： 10.1097/BS9.0000000000000241
ISSN：

关键词： Hematological disorders Metagenomic next generation sequencing

摘要：
Infections are frequent complications in patients with hematological disorders, and pathogen diagnosis remains challenging. Metagenomic next-generation sequencing (mNGS) is an unbiased high-throughput technology that has been widely applied in the diagnosis of infectious diseases. However, to date, there are no established international guidelines or expert consensuses regarding the use of mNGS to diagnose infections in patients with hematologic disorders. The Anti-Infection Study Group of the Chinese Society of Hematology invited experts in the fields of hematology, microbiology, and mNGS technology to draft an expert consensus focused on clinical indications, sample collection, quality control, and interpretation of results. This consensus will likely contribute to clarifying the medical indications for mNGS testing, optimizing the interpretation of reports, and becoming an inspiration for global practice.

基金：
Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences [2021-I2M-1-017, 2023-I2M-2-007]; National Natural Sciences Foundation of China [82470208]; National Key R&D Program of China [2024YFC2510500]
语种：
外文
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2025]版：
大类 | 4 区 医学
小类 | 4 区 血液学
最新[2025]版：
大类 | 4 区 医学
小类 | 4 区 血液学
JCR分区：
出版当年[2024]版：
Q2 HEMATOLOGY
最新[2024]版：
Q2 HEMATOLOGY

影响因子： 最新[2024版] 最新五年平均 出版当年[2024版] 出版当年五年平均 出版前一年[2024版]

第一作者：
第一作者机构： [1]Natl Clin Res Ctr Blood Dis, Inst Hematol, State Key Lab Expt Hematol, Haihe Lab Cell Ecosyst, Tianjin 300020, Peoples R China [2]Blood Dis Hosp, Tianjin 300020, Peoples R China
共同第一作者：
通讯作者：
通讯机构： [1]Natl Clin Res Ctr Blood Dis, Inst Hematol, State Key Lab Expt Hematol, Haihe Lab Cell Ecosyst, Tianjin 300020, Peoples R China [2]Blood Dis Hosp, Tianjin 300020, Peoples R China [*1]Chinese Acad Med Sci & Peking Union Med Coll, State Key Lab Expt Hematol, Natl Clin Res Ctr Blood Dis, Inst Hematol,Haihe Lab Cell Ecosyst, Tianjin 300020, Peoples R China [*2]Chinese Acad Med Sci & Peking Union Med Coll, Blood Dis Hosp, Tianjin 300020, Peoples R China
推荐引用方式(GB/T 7714)：
Xu Chunhui,Lin Ren,Bai Ye,et al.China Expert consensus on the application of metagenomic next-generation sequencing for the etiological diagnosis of infections in hematological disorders (2024)[J].BLOOD SCIENCE.2025,7(3):doi:10.1097/BS9.0000000000000241.
APA：
Xu, Chunhui,Lin, Ren,Bai, Ye,Han, Yanqiu,Hu, Jianda...&Liu, Qifa.(2025).China Expert consensus on the application of metagenomic next-generation sequencing for the etiological diagnosis of infections in hematological disorders (2024).BLOOD SCIENCE,7,(3)
MLA：
Xu, Chunhui,et al."China Expert consensus on the application of metagenomic next-generation sequencing for the etiological diagnosis of infections in hematological disorders (2024)".BLOOD SCIENCE 7..3(2025)

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