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Metagenomic Next-Generation Sequencing (mNGS) for the Timely Diagnosis of Carbapenem-Resistant Klebsiella pneumoniae in Leukemia Patients

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机构: [1]Sichuan Univ, Dept Hematol, West China Hosp, Chengdu, Peoples R China [2]Zigong First Peoples Hosp, Dept Hematol, Zigong, Sichuan, Peoples R China [3]Sichuan Canc Hosp, Dept Oncol, Chengdu, Peoples R China
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This report shows the contribution of metagenomic next-generation sequencing (mNGS) as an alternative to challenging diagnostic infection in immunosuppressed individuals. Herein, we report two leukemia patients who developed severe infections due to carbapenem-resistant Klebsiella pneumoniae (CrKP). The mNGS can be strongly recommended as an alternative investigation for patients who are at high risk of infection without positivity on body fluid culture. This can provide the opportunity for adequate therapy.

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基金编号: 2020HXFH020

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最新[2023]版:
Q4 INFECTIOUS DISEASES

影响因子: 最新[2023版] 最新五年平均 出版当年[2022版] 出版当年五年平均 出版前一年[2021版] 出版后一年[2023版]

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第一作者机构: [1]Sichuan Univ, Dept Hematol, West China Hosp, Chengdu, Peoples R China
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